Evidence map›Paper›PMID 32578043›Full record

ArticleDigestive diseases and sciences2021

Social Support Does Not Modify the Risk of Readmission for Patients with Decompensated Cirrhosis.

Jeremy Louissaint, Chelsey Foster, Emily Harding-Theobald, Anna S Lok, Elliot B Tapper

Open access · greenAbstract read
In one paragraph

Article in Digestive diseases and sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jeremy LouissaintDivision of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, 3912 Taubman, SPC 5362 1500 E Medical Center Dr., Ann Arbor, MI, 48109, USA. jelouiss@med.umich.edu.ORCID http://orcid.org/0000-0003-1154-1825
Chelsey FosterDivision of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, 3912 Taubman, SPC 5362 1500 E Medical Center Dr., Ann Arbor, MI, 48109, USA.
Emily Harding-TheobaldDivision of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, 3912 Taubman, SPC 5362 1500 E Medical Center Dr., Ann Arbor, MI, 48109, USA.
Anna S LokDivision of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, 3912 Taubman, SPC 5362 1500 E Medical Center Dr., Ann Arbor, MI, 48109, USA.
Elliot B TapperDivision of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, 3912 Taubman, SPC 5362 1500 E Medical Center Dr., Ann Arbor, MI, 48109, USA.
University of Michigan · US

Funding

Training Program in Gastrointestinal EpidemiologyT32DK062708 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Peter D.R. Higgins, Elliot Tapper · 2003 to 2026
$3.9M
Optimizing Measures for Clinical Trials in Covert Hepatic EncephalopathyK23DK117055 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TAPPER, ELLIOT · 2019 to 2022
$776k
NIDDK NIH HHS K23 DK117055NIDDK NIH HHS T32 DK062708
6 · The paper itself

Abstract

backgroundPatients with decompensated cirrhosis are at high risk of frequent hospitalizations. Whether the level of perceived social support impacts this risk is unknown. We sought to determine the relationship between social support and burden of hospitalization in patients with decompensated cirrhosis.

methodsA total of 73 patients, all with decompensated cirrhosis and an index cirrhosis-related admission between 7/1/2017 and 7/1/2019, completed the modified medical outcomes study social support (mMOS-SS) survey. We retrospectively assessed the relationship between mMOS-SS scores and probability of readmission 90-days after the index admission. Additionally, we prospectively analyzed the association between mMOS-SS scores at enrollment and risk of 90-day hospitalization.

resultsAt enrollment, 50.7% were female, median age 61 years, and median mMOS-SS score was 87.5. Median model for end-stage liver disease sodium (MELD-Na) at the time of the index admission was 15 and was 13 at the time of enrollment. The mMOS-SS score did not modify the rate of readmission 90 days after the index admission date (adjusted HR 1.01, 95%CI 0.98-1.03) nor was it associated with the rate of admission 90 days after enrollment prospectively (adjusted HR 0.99, 95%CI 0.96-1.02). The MELD-Na score at enrollment was the only significant predictor of hospitalization during prospective follow-up (adjusted HR 1.18, 95%CI 1.09-1.27).

conclusionsSocial support, as measured by the mMOS-SS survey, in patients with decompensated cirrhosis was high. However, this did not modify the risk of cirrhosis-related hospitalizations. Future investigation to define the specific components of social support that could modify readmission risk is needed.

Indexed as

Social SupportAgedCohort StudiesFemaleHumansLiver CirrhosisMaleMiddle AgedPatient ReadmissionProspective StudiesRetrospective StudiesRisk FactorsCirrhosisMELD scoreOutcomesSocial support

Identifiers

PMID32578043
PMCPMC7755706
OpenAlexW3038034654

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.