ArticleEuropean heart journal2020
ACE2 is on the X chromosome: could this explain COVID-19 gender differences?
Article in European heart journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission.Nature communications · 2020Pooled it
- Gender Characteristics of the Novel Coronavirus Infection (COVID-19) in Middle-Aged Adults.Sovremennye tekhnologii v meditsine · 2021Trial
- Profiling of proteases involved in SARS-CoV-2 pathogenesis in human saliva: Influence of age and gender.Journal, genetic engineering & biotechnology · 2025Article
- A Machine Learning-Based Web Tool for the Severity Prediction of COVID-19.Biotech (Basel (Switzerland)) · 2024Article
- SARS-CoV-2 Infection, Sex-Related Differences, and a Possible Personalized Treatment Approach with Valproic Acid: A Review.Biomedicines · 2022Review
- Hormone Therapy in the Era of the COVID-19 Pandemic: A Review.Journal of menopausal medicine · 2022Review
- Determinants of soluble angiotensin-converting enzyme 2 concentrations in adult patients with complex congenital heart disease.Clinical research in cardiology : official journal of the German Cardiac Society · 2022Article
- The Identikit of Patient at Risk for Severe COVID-19 and Death: The Dysregulation of Renin-Angiotensin System as the Common Theme.Journal of clinical medicine · 2021Review
- The severity of SARS-CoV-2 infection is dictated by host factors? Epigenetic perspectives.Current research in microbial sciences · 2021Review
- The hidden interplay between sex and COVID-19 mortality: the role of cardiovascular calcification.GeroScience · 2021Article
- COVID-19 is not "just another flu": a real-life comparison of severe COVID-19 and influenza in hospitalized patients in Vienna, Austria.Infection · 2021Article
- Gastrointestinal symptoms, pathophysiology, and treatment in COVID-19.Genes & diseases · 2021Review
- Sex differences in clinical characteristics and risk factors for disease severity of hospitalized patients with COVID-19.MedComm · 2021Article
- Monocyte activation in systemic Covid-19 infection: Assay and rationale.EBioMedicine · 2020Review
- Understanding COVID-19: in the end it is the endothelium-what else?European heart journal · 2020Article
- Men more vulnerable to COVID-19: explained by ACE2 on the X chromosome?European heart journal · 2020Article
- Immunity, Sex Hormones, and Environmental Factors as Determinants of COVID-19 Disparity in Women.Frontiers in immunologyReview
Corrections and comments
- Commented on by
- Comment on
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.