Evidence map›Paper›PMID 32577690›Full record

ArticlemedRxiv : the preprint server for health sciences2020

Jorge da Rocha, Houcemeddine Othman, Caroline T Tiemessen, Gerrit Botha, Michèle Ramsay, Collen Masimirembwa, Clement Adebamowo, Ananyo Choudhury, Jean-Tristan Brandenburg, Mogomotsi Matshaba and 4 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 6 countries.

Jorge da RochaSydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Houcemeddine OthmanSydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Caroline T TiemessenCentre for HIV and STIs, National Institute for Communicable Diseases, National Health Laboratory Services and Faculty of Health Sciences, University of the Witwatersrand, Johannesburg South Africa.
Gerrit BothaComputational Biology Division and H3ABioNet, Department of Integrative Biomedical Sciences, University of Cape Town, South Africa.
Michèle RamsaySydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Collen MasimirembwaSydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Clement AdebamowoInstitute for Human Virology, Abuja, Nigeria.
Ananyo ChoudhurySydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Jean-Tristan BrandenburgSydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Mogomotsi MatshabaBotswana-Baylor Children's Clinical Center of Excellence, Gaborone, Botswana.
Gustave SimoMolecular Parasitology and Entomology Unit, Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon.
Francisco-Javier GamoGlobal Health, GlaxoSmithKline R&D, Madrid, Spain.
Scott HazelhurstSchool of Electrical & Information Engineering, University of the Witwatersrand, Johannesburg, South Africa.
H3Africa Consortium
University of the Witwatersrand · ZANational Health Laboratory Service · ZABaylor College of Medicine · USGlaxoSmithKline (Spain) · ESUniversité de Dschang · CMUniversity of Cape Town · ZAUniversity of Maryland, Baltimore · US

Funding

The Human Genome Sequencing CenterU54HG003273 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI GIBBS, RICHARD A · 2004 to 2015
$341.3M
Shared Core: Biobanking, Bioinformatics and Data ManagementU54HG006938 · NHGRI · WITS HEALTH CONSORTIUM (PTY), LTD · PI RAMSAY, MICHELE MICHELE · 2012 to 2022
$12.2M
Phenotyping and BioarchivingU54AI110398 · NIAID · BOTSWANA BAYLOR CHILD/CLINCAL CTR/EXCELL · PI MATSHABA, MOGOMOTSI SANDY · 2014 to 2021
$8.9M
NHGRI NIH HHS U54 HG003273NHGRI NIH HHS U54 HG006938NIAID NIH HHS U54 AI110398Wellcome Trust
6 · The paper itself

Abstract

Chloroquine/hydroxychloroquine have been proposed as potential treatments for COVID-19. These drugs have warning labels for use in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Analysis of whole-genome sequence data of 458 individuals from sub-Saharan Africa showed significant

Identifiers

PMID32577690
PMCPMC7302299
OpenAlexW3028710493

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.