Evidence map›Paper›PMID 32577654›Full record

ArticlebioRxiv : the preprint server for biology2020

Landscape and Selection of Vaccine Epitopes in SARS-CoV-2.

Christof C Smith, Sarah Entwistle, Caryn Willis, Steven Vensko, Wolfgang Beck, Jason Garness, Maria Sambade, Eric Routh, Kelly Olsen, Julia Kodysh and 10 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 25 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 1 country.

Christof C SmithDepartment of Microbiology and Immunology, UNC School of Medicine, Chapel Hill, North Carolina.
Sarah EntwistleLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Caryn WillisLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Steven VenskoLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Wolfgang BeckDepartment of Microbiology and Immunology, UNC School of Medicine, Chapel Hill, North Carolina.
Jason GarnessLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Maria SambadeLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Eric RouthLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Kelly OlsenDepartment of Microbiology and Immunology, UNC School of Medicine, Chapel Hill, North Carolina.
Julia KodyshDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.
Timothy O'DonnellDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.
Carsten HaberPEPperPRINT GmbH, Heidelberg, Germany.
Kirsten HeissPEPperPRINT GmbH, Heidelberg, Germany.
Volker StadlerPEPperPRINT GmbH, Heidelberg, Germany.
Erik GarrisonGenomics Institute, University of California, Santa Cruz, California.
Oliver C GrantComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia.
Robert J WoodsComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia.
Mark HeiseLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Benjamin G VincentDepartment of Microbiology and Immunology, UNC School of Medicine, Chapel Hill, North Carolina.
Alex RubinsteynLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
University of North Carolina at Chapel Hill · USIcahn School of Medicine at Mount Sinai · USUniversity of Georgia · USUniversity of California, Santa Cruz · US

Funding

Design and Delivery of Neoantigen-based Tumor VaccinesF30CA225136 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SMITH, CHRISTOF CHIU · 2018 to 2021
$142k
NCI NIH HHS F30 CA225136
6 · The paper itself

Abstract

There is an urgent need for a vaccine with efficacy against SARS-CoV-2. We hypothesize that peptide vaccines containing epitope regions optimized for concurrent B cell, CD4

Identifiers

PMID32577654
PMCPMC7302209
OpenAlexW3033590859

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.