Evidence map›Paper›PMID 32577297›Full record

ArticleMultiple sclerosis journal - experimental, translational and clinical

Upper limb entrapment neuropathies in multiple sclerosis.

Han Yin, Krishnan Ps Nair, Dasappaiah G Rao, Sankaranarayanan Hariharan, Amy Spencer, Kathleen Baster

Open access · goldAbstract read
In one paragraph

Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Han YinNorthern General Hospital, Sheffield Teaching Hospital NHS Foundation Trust, UK.
Krishnan Ps NairRoyal Hallamshire Hospital, UK.ORCID https://orcid.org/0000-0002-4004-2315
Dasappaiah G RaoRoyal Hallamshire Hospital, UK.
Sankaranarayanan HariharanPrincess Royal Spinal Injuries Unit, Northern General Hospital, UK.
Amy SpencerStatistical Services Unit, University of Sheffield, UK.
Kathleen BasterStatistical Services Unit, University of Sheffield, UK.
Royal Hallamshire Hospital · GBRoyal Statistical Society · GBNorthern General Hospital · GBUniversity of Ulster · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEntrapment neuropathies of upper limbs such as carpal tunnel and cubital tunnel syndromes are common in the general population. Identification of entrapment neuropathies of upper limbs in patients with multiple sclerosis can be clinically challenging as signs and symptoms could be attributed to multiple sclerosis. People at later stages of multiple sclerosis use mobility aids and wheelchairs. Weakness of hands in this cohort due to entrapment neuropathies could adversely affect their mobility and independence.

methodsThis was a retrospective review of records of patients with multiple sclerosis referred for clinical neurophysiological studies with clinical suspicion of upper limb entrapment neuropathies over a 10-year period. We collected demographic details, clinical features, clinical neurophysiological data and details of aids and appliances used for mobility.

resultsAmong 71 patients, 38 (53.5%) patients had at least one entrapment neuropathy of upper limb confirmed by clinical neurophysiological studies. Twelve (31%) patients had median nerve entrapment, 20 (53%) had ulnar nerve entrapment and six (16%) had both. Risk of ulnar nerve entrapment was significantly higher in patients using a powered wheelchair (odds ratio 5.7, 95% confidence interval (1.7-18.7, DISCUSSION: Entrapment neuropathies should be considered in patients with multiple sclerosis reporting sensory and motor symptoms of hands.

Indexed as

carpal tunnel syndromecubital tunnel syndrome.entrapment neuropathiesMultiple sclerosisrehabilitationupper limb

Identifiers

PMID32577297
PMCPMC7288819
OpenAlexW3034974038

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.