Evidence map›Paper›PMID 32577217›Full record

ArticlePulmonary circulation

Exercise and fluid challenge during right heart catheterisation for evaluation of dyspnoea.

Ralf Ewert, Alexander Heine, Annegret Müller-Heinrich, Tom Bollmann, Anne Obst, Susanna Desole, Christine Knaak, Beate Stubbe, Christian F Opitz, Dirk Habedank

Open access · goldAbstract read
In one paragraph

Article in Pulmonary circulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Pulmonary hypertension associated with lung diseases.The European respiratory journal · 2024
    Review
  3. Pulmonary hypertension associated with left heart disease.The European respiratory journal · 2024
    Review
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ralf EwertDepartment of Internal Medicine B, University Hospital Greifswald, Greifswald, Germany.
Alexander HeineDepartment of Internal Medicine B, University Hospital Greifswald, Greifswald, Germany.
Annegret Müller-HeinrichDepartment of Internal Medicine B, University Hospital Greifswald, Greifswald, Germany.
Tom BollmannDepartment of Internal Medicine B, University Hospital Greifswald, Greifswald, Germany.
Anne ObstDepartment of Internal Medicine B, University Hospital Greifswald, Greifswald, Germany.
Susanna DesoleDepartment of Internal Medicine B, University Hospital Greifswald, Greifswald, Germany.
Christine KnaakDepartment of Internal Medicine B, University Hospital Greifswald, Greifswald, Germany.
Beate StubbeDepartment of Internal Medicine B, University Hospital Greifswald, Greifswald, Germany.
Christian F OpitzDRK Kliniken Berlin, Department Cardiology, Berlin, Germany.
Dirk HabedankDRK Kliniken Berlin, Department Cardiology, Berlin, Germany.ORCID https://orcid.org/0000-0003-3403-7146
Universitätsmedizin Greifswald · DEDRK Kliniken Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This prospective study compared exercise test and intravenous fluid challenge in a single right heart catheter procedure to detect latent diastolic heart failure in patients with echocardiographic heart failure with preserved ejection function. We included 49 patients (73% female) with heart failure with preserved ejection function and pulmonary artery wedge pressure ≤15 mmHg. A subgroup of 26 patients had precapillary pulmonary hypertension. Invasive haemodynamic and gas exchange parameters were measured at rest, 45° upright position, during exercise, after complete haemodynamic and respiratory recovery in lying position, and after rapid infusion of 500 mL isotonic solution. Most haemodynamic parameters increased at both exercise and intravenous fluid challenge, with the higher increase at exercise. Pulmonary vascular resistance decreased by -0.21 wood units at exercise and -0.56 wood units at intravenous fluid challenge (

Indexed as

dyspnoeaexercisefluid challengehaemodynamicright heart catheter

Identifiers

PMID32577217
PMCPMC7290273
OpenAlexW3012069671

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.