Evidence map›Paper›PMID 32577183›Full record

ArticleInternational journal of preventive medicine2020

Free Radical Production in the Smoking of E-Cigarettes and their Possible Effects in Human Health.

Roberto Menicagli, Ortensio Marotta, Roberta Serra

Open access · goldAbstract read
In one paragraph

Article in International journal of preventive medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. E‑Cigarettes Generate Gas Phase Ions.Environment & health (Washington, D.C.) · 2026
    Article
  3. Review
  4. Sex-specific lung inflammation and mitochondrial damage in a model of electronic cigarette exposure in asthma.American journal of physiology. Lung cellular and molecular physiology · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. E-Cigarette Toxicology.Annual review of pharmacology and toxicology · 2022
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Roberto MenicagliDir Roma Biomed Research Lab, Milan, Italy.
Ortensio MarottaProf University Federico II, ENT DEPT Medicine Faculty, Naples, Italy.
Roberta SerraMed Res University, Pavia, Italy.
Biomed Research Institute · USFederico II University Hospital · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe increase in smoking e-cigarettes with nicotine or only flavoring compounds requires a deep study on consequences on human health. This research aims to study the possible process, to form free radicals or the nuclei's damages with consequent micronuclei's formation.

methodsThe study analyzed three groups: the first one that uses e-cigarettes with nicotine, (e-nicotine), the second flavoured liquid (e-vapor) and third the not-smoking group. We determinated the salivary malondialdehyde (MDA), the total salivary mucins (SM). and in buccal smear cells the micronuclei (MN). We statistically analyzed the results with the Mann-Whitney U Test Calculator.

resultsSmoking e-cigarettes e-nicotine or e-vapor produced a great and significative amount of MDA vs control group:

conclusionsThis study shows the possible damages of the nuclei, but the increase of radicals, oral mucins and MN needs more researches.

Indexed as

Electronic nicotine delivery systemsfree radicalsneoplasm

Identifiers

PMID32577183
PMCPMC7297425
OpenAlexW3037777615

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.