Evidence map›Paper›PMID 32577132›Full record

ArticleTherapeutic advances in gastroenterology2020

A novel combined anorectal biofeedback and percutaneous tibial nerve stimulation protocol for treating fecal incontinence.

Yoav Mazor, Gillian M Prott, Carol Sequeira, Michael Jones, Anastasia Ejova, John E Kellow, Margaret Schnitzler, Allison Malcolm

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Effects of Tibial Nerve Electrostimulation in Patients With Fecal Incontinence: A Systematic Review.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yoav MazorDepartment of Gastroenterology, Royal North Shore Hospital, St Leonards, NSW, Australia.ORCID https://orcid.org/0000-0001-8590-6271
Gillian M ProttDepartment of Gastroenterology, Royal North Shore Hospital, St Leonards, NSW, Australia.
Carol SequeiraDepartment of Gastroenterology, Royal North Shore Hospital, St Leonards, NSW, Australia.
Michael JonesPsychology Department, Macquarie University, Sydney, NSW, Australia.
Anastasia EjovaPsychology Department, Macquarie University, Sydney, NSW, Australia.
John E KellowDepartment of Gastroenterology, Royal North Shore Hospital, St Leonards, NSW, Australia.
Margaret SchnitzlerDepartment of Colorectal Surgery, Royal North Shore Hospital, St Leonards, NSW, Australia.
Allison MalcolmDepartment of Gastroenterology, Royal North Shore Hospital, St Leonards, NSW, Australia.
The University of Sydney · AUMacquarie University · AURoyal North Shore Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsFecal incontinence (FI) is a common, debilitating condition that causes major impact on quality of life for those affected. Non-surgical treatment options include anorectal biofeedback therapy (BF) and percutaneous tibial nerve stimulation (PTNS), usually performed separately. The aims of the current study were to determine the feasibility, tolerability, safety, and efficacy of performing a combined BF and PTNS treatment protocol.

methodsFemale patients with urge FI were offered a novel pilot program combining BF with PTNS. The treatment protocol consisted of 13 weekly sessions: an educational session, followed by 5 combined BF and PTNS sessions, 6 PTNS and a final combined session. Anorectal physiology and clinical outcomes were assessed throughout the program. For efficacy, patients were compared with BF only historical FI patients matched for age, parity, and severity of symptoms.

resultsA total of 12/13 (93%) patients completed the full program. Overall attendance rate was 93% (157/169 sessions). Patient comfort score with treatment was rated high at 9.8/10 (SD 0.7) for PTNS and 8.6/10 (SD 1.7) for the BF component. No major side effects were reported. A reduction of at least 50% in FI episodes/week was achieved by 58% of patients by visit 6, and 92% by visit 13. No physiology changes were evident immediately following PTNS compared with before, but pressure during sustained anal squeeze improved by the end of the treatment course. Comparing outcomes with historical matched controls, reductions in weekly FI episodes were more pronounced in the BF only group at visit 6, but not week 13.

conclusionsIn this pilot study, concurrent PTNS and anorectal biofeedback therapy has been shown to be feasible, comfortable, and low risk. The combined protocol is likely to be an effective treatment for FI, but future research could focus on optimizing patient selection.

Indexed as

anorectalbiofeedbackincontinenceneuromodulation

Identifiers

PMID32577132
PMCPMC7288816
OpenAlexW3034250489

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.