ReviewTheScientificWorldJournal2020
Mesotherapy: From Historical Notes to Scientific Evidence and Future Prospects.
Review in TheScientificWorldJournal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- Evaluation of the Performance and Safety of a New Micro-Needle Technology in Comparison With the Classic Needle on the Antiaging Effects of a Biorevitalizing Solution: A Randomized Split Face/Neck Study.Journal of cosmetic dermatology · 2024Trial
- Efficacy of Mesotherapy for Pain, Function and Quality of Life in Patients with Mild and Moderate Knee Osteoarthritis: A Randomized Controlled Trial.Journal of musculoskeletal & neuronal interactions · 2023Trial
- Intradermal mesotherapy versus intravenous dexketoprofen for the treatment of migraine headache without aura: a randomized controlled trial.Annals of Saudi medicineTrial
- Evaluation of the Efficacy and Safety of Collagen Mesotherapy in the Course of Chronic Cervicocephalic Syndrome-A Retrospective Observational Study.Journal of clinical medicine · 2026Article
- Efficacy of mesotherapy in patients with acute and subacute neck pain: A randomized controlled trial.Turkish journal of physical medicine and rehabilitation · 2026Article
- Italian Expert Consensus on the Efficacy and Safety of High Doses of Incobotulinum Toxin A (BocoutureDermatology and therapy · 2026Review
- Clinical Efficacy of Tofacitinib in Treating Granulomatous Reaction After Mesotherapy: A Case Series Analysis.Journal of cosmetic dermatology · 2026Article
- Consensus statement on mesotherapy for clinical and regulatory practice.Rheumatology international · 2026Review
- Comparative clinical and thermographic responses to dexamethasone and saline solution mesotherapy in horses with spinal disorders.Frontiers in veterinary science · 2026Article
- Complications, Functional Recovery, and Quality of Life in Breast Cancer Patients Undergoing Axillary Surgery.The breast journal · 2026Article
- Effectiveness of a mesotherapy protocol vs. an epidural injection of platelet-rich plasma or methylprednisolone in degenerative lumbosacral stenosis in dogs - a retrospective study.Frontiers in veterinary science · 2026Article
- Efficacy and Effectiveness of High Molecular Weight Non-Cross-Linked Hyaluronic Acid Plus Succinic Acid Mesotherapy in Rosacea as Adjunct Therapy.Journal of cosmetic dermatology · 2025Article
- The role of mesotherapy in chronic back pain syndrome: what do we know?Rheumatology international · 2025Review
- A Retrospective Analysis of the Effectiveness and Safety of Collagen Mesotherapy in the Course of Chronic Cervical Myofascial Pain Syndrome.Biomedicines · 2025Article
- International Consensus Guidelines on the Safe and Evidence-Based Practice of Mesotherapy: A Multidisciplinary Statement.Journal of clinical medicine · 2025Article
- Novel Electrotrichogenic Device Promotes Hair Growth in Men With Androgenetic Alopecia: A Pilot Study.Journal of cosmetic dermatology · 2025Article
- Spinal collagen mesotherapy in patients with chronic thoracic back pain: a retrospective analysis of effectiveness and safety in a 3-month follow-up.Reumatologia · 2025Article
- The Effect of Intradermal Injection with Two Different Injection Techniques on Pain and Functional Status in Patients with Chronic Nonspecific Neck Pain.Medeniyet medical journal · 2024Article
- Upper Crossed Syndrome and Scapulae Upper-Trapping: A Mesotherapy Protocol in Cervicoscapulobrachial Pain-The 8:1 Block.Bioengineering (Basel, Switzerland) · 2024Article
- Platelet-Rich Plasma for the Treatment of Atopic Dermatitis: A Literature Review.The Journal of clinical and aesthetic dermatology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intradermal therapy, known as mesotherapy, is a technique used to inject a drug into the surface layer of the skin. In particular, it involves the use of a short needle to deposit the drug in the dermis. The intradermal microdeposit modulates the drug's kinetics, slowing absorption and prolonging the local mechanism of action. It is successfully applied in the treatment of some forms of localized pain syndromes and other local clinical conditions. It could be suggested when a systemic drug-sparing effect is useful, when other therapies have failed (or cannot be used), and when it can synergize with other pharmacological or nonpharmacological therapies. Despite the lack of randomized clinical trials in some fields of application, a general consensus is also reached in nonpharmacological mechanism of action, the technique execution modalities, the scientific rationale to apply it in some indications, and the usefulness of the informed consent. The Italian Mesotherapy Society proposes this position paper to apply intradermal therapy based on scientific evidence and no longer on personal bias.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.