Evidence map›Paper›PMID 32577068›Full record

ArticleJournal of human reproductive sciences

Impact of Serum Human Chorionic Gonadotropin and Luteinizing Hormone Receptor Expression to Oocyte Maturation Rate: A Study of Controlled Ovarian Stimulation.

Hilwah Nora, Budi Wiweko, R Muharam, Rajuddin, Grace Wangge, Andon Hestiantoro, Gita Pratama, Achmad Kemal Harzif, Sarah Chairani Zakirah

Open access · diamondAbstract read
In one paragraph

Article in Journal of human reproductive sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Hilwah NoraDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Syiah Kuala, Banda Aceh, Indonesia.
Budi WiwekoDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia, Indonesia.
R MuharamDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia, Indonesia.
RajuddinDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Syiah Kuala, Banda Aceh, Indonesia.
Grace WanggeSoutheast Asia Ministers of Education Regional Centre for Food and Nutrition - Pusat Kajian Gizi Regional, University of Indonesia, Central Jakarta, Indonesia.
Andon HestiantoroDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia, Indonesia.
Gita PratamaDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia, Indonesia.
Achmad Kemal HarzifDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia, Indonesia.
Sarah Chairani ZakirahDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Indonesia, Indonesia.
Education and Research Institute · USUniversity of Indonesia · IDMinistry of Education and Culture · IDRumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo · IDSyiah Kuala University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFew studies have assessed the impact of serum human chorionic gonadotropin (hCG) levels before oocyte retrieval and luteinizing hormone receptor (LHR) mRNA expression.

aimsThe objective was to assess the correlations between serum hCG levels at 12-h posttrigger granulosa cell LHR mRNA expression during the SETTINGS AND

designA cross-sectional was conducted for this study at the IVF center of Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia. MATERIALS AND

methodsRecombinant follicle-stimulating hormone was used on day 2 of the menstrual cycle with multiple doses of a gonadotropin-releasing hormone antagonist. Recombinant hCG was used to trigger ovulation. At 12-h posttrigger, hCG serum levels were measured using an enzyme-linked immunosorbent assay. STATISTICAL ANALYSIS: Pearson's correlation coefficient was used to evaluate the correlation between oocyte maturation rates, serum hCG levels, and LHR mRNA levels. Cutoff values were determined using a receiver operating characteristic (ROC) curve.

resultsSerum hCG levels were positively correlated (

conclusionOocyte maturation is correlated with serum hCG levels with 77 mIU/mL as the cutoff point for oocyte retrieval.

Indexed as

Cutoff valuehuman chorionic gonadotropinluteinizing hormone receptoroocyte maturationposttrigger

Identifiers

PMID32577068
PMCPMC7295261
OpenAlexW3015376473

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.