Evidence map›Paper›PMID 32576932›Full record

ArticleScientific reports2020

Synergistic stabilization by nitrosoglutathione-induced thiol modifications in the stromal interaction molecule-2 luminal domain suppresses basal and store operated calcium entry.

Matthew J Novello, Jinhui Zhu, MengQi Zhang, Qingping Feng, Peter B Stathopulos

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Oxidative protein folding and CaCellular and molecular life sciences : CMLS · 2026
    Review
  2. Review
  3. Review
  4. Review
  5. Multifaceted control of T cell differentiation by STIM1.Trends in biochemical sciences · 2023
    Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Matthew J NovelloDepartment of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, the University of Western Ontario, London, Ontario, N6A5C1, Canada.
Jinhui ZhuDepartment of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, the University of Western Ontario, London, Ontario, N6A5C1, Canada.
MengQi ZhangDepartment of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, the University of Western Ontario, London, Ontario, N6A5C1, Canada.
Qingping FengDepartment of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, the University of Western Ontario, London, Ontario, N6A5C1, Canada. qfeng@uwo.ca.
Peter B StathopulosDepartment of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, the University of Western Ontario, London, Ontario, N6A5C1, Canada. pstatho@uwo.ca.
Western University · CA

Funding

CIHR MOP-142383
6 · The paper itself

Abstract

Stromal interaction molecule-1 and -2 (STIM1/2) are endoplasmic reticulum (ER) membrane-inserted calcium (Ca

Indexed as

CalciumCalcium SignalingCell LineCell MembraneEndoplasmic ReticulumGlutathioneHEK293 CellsHumansMembrane ProteinsORAI1 ProteinProtein BindingStromal Interaction Molecule 1Stromal Interaction Molecule 2Sulfhydryl CompoundsCalciumGlutathioneMembrane ProteinsORAI1 ProteinSTIM2 protein, humanStromal Interaction Molecule 1Stromal Interaction Molecule 2Sulfhydryl Compounds

Identifiers

PMID32576932
PMCPMC7311479
OpenAlexW3035890451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.