ArticleScientific reports2020
Heritability and genome-wide association of swine gut microbiome features with growth and fatness parameters.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed, 124 citations in OpenAlex.
- Associations of host gene expression in the brain, liver, muscle with fecal and cecal microbiota composition in pigs.Functional & integrative genomics · 2026Article
- Host-Microbiota Interactions in the Regulation of Intestinal Health in Weaned Piglets: Molecular Mechanisms and Nutritional Intervention Strategies.Animals : an open access journal from MDPI · 2026Review
- Integrated analyses of host genetics and gut microbiota provide mechanistic insights into feed efficiency in ducks.Journal of animal science and biotechnology · 2026Article
- Microbial and Genomic Information Synergistically Contribute to Predicting Swine Performance Across Production Systems.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2026Article
- Unraveling the role of bacteria with heritable versus non-heritable relative abundance in the gut on boar semen quality.Genetics, selection, evolution : GSE · 2025Article
- Incorporating transcriptomic data into genomic prediction models to improve the prediction accuracy of phenotypes of efficiency traits.Genetics, selection, evolution : GSE · 2025Article
- One Function, Many Faces: Functional Convergence in the Gut Microbiomes of European Marine and Freshwater Fish Unveiled by Bayesian Network Meta-Analysis.Animals : an open access journal from MDPI · 2025Article
- Fecal microbiota transplantation in pigs: current status and future perspective.Animal microbiome · 2025Review
- Variation of Meat Quality and Relationship to Gut Microbiota Among Different Pig Breeds.Microbial biotechnology · 2025Article
- Metabolic pathways associated with Firmicutes prevalence in the gut of multiple livestock animals and humans.Animal microbiome · 2025Article
- Characterization of microbiota signatures in Iberian pig strains using machine learning algorithms.Animal microbiome · 2025Article
- Effects of probiotics on growth performance, intestinal morphology, intestinal microbiota weaning pig challenged withJournal of animal science and technology · 2025Article
- Multiple-trait genomic prediction for swine meat quality traits using gut microbiome features as a correlated trait.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2025Article
- Effect of feeding a gestation diet to sows for 5 days post-farrowing and feeding a liquid mixture of milk replacer and starter diet to suckling piglets on growth, selected health parameters and faecal microbiota of suckling pigs on two research farms.Translational animal science · 2025Article
- Estimates of microbiome heritability across hosts.Nature microbiology · 2024Review
- Effects of Dietary Net Energy Concentration on Reproductive Performance, Immune Function, Milk Composition, and Gut Microbiota in Primiparous Lactating Sows.Animals : an open access journal from MDPI · 2024Article
- Parameter Estimation of Host Genomic and Gut Microbiota Contribution to Growth and Feed Efficiency Traits in Meat Rabbits.Microorganisms · 2024Article
- Microbial and Metabolic Profiling of Obese and Lean Luchuan Pigs: Implications for Phenotypic Divergence.Animals : an open access journal from MDPI · 2024Article
- Rational management of the plant microbiome for the Second Green Revolution.Plant communications · 2024Review
- Including microbiome information in a multi-trait genomic evaluation: a case study on longitudinal growth performance in beef cattle.Genetics, selection, evolution : GSE · 2024Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite recent efforts to characterize longitudinal variation in the swine gut microbiome, the extent to which a host's genome impacts the composition of its gut microbiome is not yet well understood in pigs. The objectives of this study were: i) to identify pig gut microbiome features associated with growth and fatness, ii) to estimate the heritability of those features, and, iii) to conduct a genome-wide association study exploring the relationship between those features and single nucleotide polymorphisms (SNP) in the pig genome. A total of 1,028 pigs were characterized. Animals were genotyped with the Illumina PorcineSNP60 Beadchip. Microbiome samples from fecal swabs were obtained at weaning (Wean), at mid-test during the growth trial (MidTest), and at the end of the growth trial (OffTest). Average daily gain was calculated from birth to week 14 of the growth trial, from weaning to week 14, from week 14 to week 22, and from week 14 to harvest. Backfat and loin depth were also measured at weeks 14 and 22. Heritability estimates (±SE) of Operational Taxonomic Units ranged from 0.025 (±0.0002) to 0.139 (±0.003), from 0.029 (±0.003) to 0.289 (±0.004), and from 0.025 (±0.003) to 0.545 (±0.034) at Wean, MidTest, and OffTest, respectively. Several SNP were significantly associated with taxa at the three time points. These SNP were located in genomic regions containing a total of 68 genes. This study provides new evidence linking gut microbiome composition with growth and carcass traits in swine, while also identifying putative host genetic markers associated with significant differences in the abundance of several prevalent microbiome features.
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