Evidence map›Paper›PMID 32576679›Full record

ArticleScience signaling2020

TRPML1ng on sparks.

Madeline Nieves-Cintron, Luis F Santana, Manuel F Navedo

Open access · greenAbstract readComment
In one paragraph

Article in Science signaling, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Lysosomal CaCirculation. Arrhythmia and electrophysiology · 2025
    Article
  2. Article
  3. Lysosomal CaPNAS nexus · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Madeline Nieves-CintronDepartment of Pharmacology, University of California Davis, Davis, CA 95616, USA.ORCID 0000-0003-1935-8400
Luis F SantanaDepartment of Physiology and Membrane Biology, University of California Davis, Davis, CA 95616, USA.
Manuel F NavedoDepartment of Pharmacology, University of California Davis, Davis, CA 95616, USA. mfnavedo@ucdavis.edu.ORCID 0000-0001-6864-6594
University of California, Davis · US

Funding

Coupling of Vascular Cav1.2 Channels In Health & DiseaseR01HL121059 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI NAVEDO, MANUEL F · 2015 to 2024
$4.5M
Calcium Sparklets-Induced Vascular Dysfunction During DiabetesR01HL098200 · NHLBI · UNIVERSITY OF WASHINGTON · PI NAVEDO, MANUEL F · 2010 to 2019
$3.5M
Cerebral Vascular Smooth Muscle Dysfunction in Alzheimer's DiseaseR01HL149127 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI NAVEDO, MANUEL F · 2019 to 2022
$2.7M
Tuning L-Type Ca Channel Activity in Arterial Smooth Muscle by Kv Channel-Mediated ClusteringR01HL144071 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SANTANA, LUIS F, TRIMMER, JAMES S · 2018 to 2021
$2.0M
NHLBI NIH HHS R01 HL098200NHLBI NIH HHS R01 HL121059NHLBI NIH HHS R01 HL144071NHLBI NIH HHS R01 HL149127
6 · The paper itself

Abstract

In this issue of

Indexed as

CalciumCalcium SignalingMuscle, Smooth, VascularMyocytes, Smooth MuscleRyanodine Receptor Calcium Release ChannelCalciumRyanodine Receptor Calcium Release Channel

Identifiers

PMID32576679
PMCPMC7384335
OpenAlexW3036003348

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.