Evidence map›Paper›PMID 32576674›Full record

ArticlemBio2020

Widespread Strain-Specific Distinctions in Chromosomal Binding Dynamics of a Highly Conserved Escherichia coli Transcription Factor.

James P R Connolly, Nicky O'Boyle, Andrew J Roe

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Distinct ecological fitness factors coordinated by a conservedProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

James P R ConnollyNU Biosciences Institute, Newcastle University, Newcastle-upon-Tyne, United Kingdom James.Connolly2@newcastle.ac.uk Andrew.Roe@glasgow.ac.uk.ORCID 0000-0002-0394-3413
Nicky O'BoyleInstitute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Andrew J RoeInstitute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom James.Connolly2@newcastle.ac.uk Andrew.Roe@glasgow.ac.uk.ORCID 0000-0003-3698-6134
University of Glasgow · GBNewcastle University · GB

Funding

Biotechnology and Biological Sciences Research Council BB/M029646/1Biotechnology and Biological Sciences Research Council BB/R006539/1
6 · The paper itself

Abstract

Bacterial gene regulation is governed by often hundreds of transcription factors (TFs) that bind directly to targets on the chromosome. Global studies of TFs usually make assumptions that regulatory targets within model strains will be conserved between members of the same species harboring common genetic targets. We recently discovered that YhaJ of

Indexed as

Binding SitesChromosomes, BacterialEscherichia coliEscherichia coli ProteinsEvolution, MolecularGene Expression Regulation, BacterialGenes, RegulatorGenome, BacterialPhylogenyTranscription FactorsEscherichia coli ProteinsTranscription FactorsChIP-seqE. coliregulationtranscription factor

Identifiers

PMID32576674
PMCPMC7315121
OpenAlexW3036934864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.