Evidence map›Paper›PMID 32576672›Full record

ArticlemBio2020

Dectin-1 Stimulation of Hematopoietic Stem and Progenitor Cells Occurs

Cristina Bono, Alba Martínez, Javier Megías, Daniel Gozalbo, Alberto Yáñez, M Luisa Gil

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trained Immunity in Childhood Vaccination.Acta paediatrica (Oslo, Norway : 1992) · 2026
    Review
  2. Article
  3. Article
  4. Hematopoietic stem cell state and fate in trained immunity.Cell communication and signaling : CCS · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Journal of fungi (Basel, Switzerland) · 2022
    Article
  9. Review
  10. Review
  11. Article
  12. From structure to function - Ligand recognition by myeloid C-type lectin receptors.Computational and structural biotechnology journal · 2022
    Review
  13. Review
  14. Review
  15. Article
  16. Trained Immunity as an Adaptive Branch of Innate Immunity.International journal of molecular sciences · 2021
    Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Cristina BonoDepartamento de Microbiología y Ecología, Universitat de València, Burjassot, Spain.
Alba MartínezDepartamento de Microbiología y Ecología, Universitat de València, Burjassot, Spain.
Javier MegíasDepartamento de Patología, Universitat de València, Valencia, Spain.
Daniel GozalboDepartamento de Microbiología y Ecología, Universitat de València, Burjassot, Spain.
Alberto YáñezDepartamento de Microbiología y Ecología, Universitat de València, Burjassot, Spain.ORCID 0000-0002-7719-1963
M Luisa GilDepartamento de Microbiología y Ecología, Universitat de València, Burjassot, Spain m.luisa.gil@uv.es.ORCID 0000-0003-0319-5678
Universitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toll-like receptor (TLR) agonists drive hematopoietic stem and progenitor cells (HSPCs) to differentiate along the myeloid lineage. In this study, we used an HSPC transplantation model to investigate the possible direct interaction of β-glucan and its receptor (dectin-1) on HSPCs

Indexed as

Cell DifferentiationAnimalsbeta-GlucansCandida albicansCandidiasisDectin-1FemaleHematopoietic Stem CellsImmunity, InnateLectins, C-TypeMacrophagesMaleMiceMice, Inbred C57BLMice, KnockoutMyeloid Differentiation Factor 88beta-GlucansDectin-1Lectins, C-TypeMyd88 protein, mouseMyeloid Differentiation Factor 88Tlr2 protein, mouseToll-Like Receptor 2Candida albicansdectin-1hematopoietic stem and progenitor cellsmacrophagesTLR2trained immunity

Identifiers

PMID32576672
PMCPMC7315119
OpenAlexW3036645778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.