Evidence map›Paper›PMID 32576667›Full record

ArticleJournal of cell science2020

H3K9me3 maintenance on a human artificial chromosome is required for segregation but not centromere epigenetic memory.

Nuno M C Martins, Fernanda Cisneros-Soberanis, Elisa Pesenti, Natalia Y Kochanova, Wei-Hao Shang, Tetsuya Hori, Takahiro Nagase, Hiroshi Kimura, Vladimir Larionov, Hiroshi Masumoto and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of cell science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Nuno M C MartinsWellcome Trust Centre for Cell Biology, Edinburgh, UK.ORCID 0000-0003-3953-9313
Fernanda Cisneros-SoberanisWellcome Trust Centre for Cell Biology, Edinburgh, UK.ORCID 0000-0003-1120-1695
Elisa PesentiWellcome Trust Centre for Cell Biology, Edinburgh, UK.ORCID 0000-0002-1958-5411
Natalia Y KochanovaWellcome Trust Centre for Cell Biology, Edinburgh, UK.ORCID 0000-0001-9951-8333
Wei-Hao ShangGraduate School of Frontier Biosciences, Osaka University, Osaka, Japan.
Tetsuya HoriGraduate School of Frontier Biosciences, Osaka University, Osaka, Japan.
Takahiro NagaseKazusa DNA Research Institute, Kisarazu, Japan.
Hiroshi KimuraCell Biology Unit, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.ORCID 0000-0003-0854-083X
Vladimir LarionovNational Cancer Institute, National Institutes of Health, Bethesda, USA.
Hiroshi MasumotoKazusa DNA Research Institute, Kisarazu, Japan.
Tatsuo FukagawaGraduate School of Frontier Biosciences, Osaka University, Osaka, Japan.ORCID 0000-0001-8564-6852
William C EarnshawWellcome Trust Centre for Cell Biology, Edinburgh, UK bill.earnshaw@ed.ac.uk.ORCID 0000-0002-7191-0621
Wellcome Centre for Cell Biology · GBUbe Frontier University · JPKazusa DNA Research Institute · JPNational Institutes of Health · USTokyo Institute of Technology · JP

Funding

Study of hereditary prostate cancer and human artificial chromosomesZIABC010413 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LARIONOV, VLADIMIR · 2009 to 2025
$31.5M
Biotechnology and Biological Sciences Research Council BB/M018040/1Wellcome TrustWellcome Trust 073915Wellcome Trust 077707Wellcome Trust 092076
6 · The paper itself

Abstract

Most eukaryotic centromeres are located within heterochromatic regions. Paradoxically, heterochromatin can also antagonize

Indexed as

Chromosomes, Artificial, HumanCentromereCentromere Protein AChromosome SegregationEpigenesis, GeneticHeterochromatinHistonesHumansJumonji Domain-Containing Histone DemethylasesKinetochoresCentromere Protein AHeterochromatinHistonesJumonji Domain-Containing Histone DemethylasesKDM4D protein, humanCENP-ACentromereEpigenetic engineeringHeterochromatinHuman artificial chromosomeKinetochoreMitosisPolycomb

Identifiers

PMID32576667
PMCPMC7390644
OpenAlexW3036171973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.