Evidence map›Paper›PMID 32576622›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Discharge and Role of GABA Pontomesencephalic Neurons in Cortical Activity and Sleep-Wake States Examined by Optogenetics and Juxtacellular Recordings in Mice.

Youssouf Cissé, Masaru Ishibashi, Josefa Jost, Hanieh Toossi, Lynda Mainville, Antoine Adamantidis, Christopher S Leonard, Barbara E Jones

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Diverse Firing Profiles ofThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Youssouf CisséDepartment of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec H3A 2B4, Canada.
Masaru IshibashiDepartment of Physiology, New York Medical College, Valhalla, New York 10595.ORCID 0000-0002-7413-1359
Josefa JostDepartment of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec H3A 2B4, Canada.
Hanieh ToossiDepartment of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec H3A 2B4, Canada.
Lynda MainvilleDepartment of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec H3A 2B4, Canada.
Antoine AdamantidisDepartment of Biomedical Research and Department of Neurology, Zentrum Für Experimentelle Neurologie, Inselspital University Hospital Bern, University of Bern, Bern 3010, Switzerland.
Christopher S LeonardDepartment of Physiology, New York Medical College, Valhalla, New York 10595.ORCID 0000-0003-4414-1748
Barbara E JonesDepartment of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec H3A 2B4, Canada barbara.jones@mcgill.ca.ORCID 0000-0001-9985-3860
Montreal Neurological Institute and Hospital · CANew York Medical College · USUniversity of Bern · CH

Funding

"Synaptic Modulation of Mesopontine Cholingergic Neurons"R01NS027881 · NINDS · NEW YORK UNIVERSITY · PI LEONARD, CHRISTOPHER S · 1992 to 2022
$7.1M
CIHR MOP130502CIHR MOP246264NINDS NIH HHS R01 NS027881
6 · The paper itself

Abstract

The cholinergic neurons in the pontomesencephalic tegmentum have been shown to discharge in association with and promote cortical activation during active or attentive waking and paradoxical or rapid eye movement sleep. However, GABA neurons lie intermingled with the cholinergic neurons and may contribute to or oppose this activity and role. Here we investigated

Indexed as

AnesthesiaAnimalsCerebral CortexElectroencephalographyElectrophysiological PhenomenaFemalegamma-Aminobutyric AcidMaleMesencephalonMiceMice, Inbred C57BLMice, TransgenicOptogeneticsPhotic StimulationPonsSleepgamma-Aminobutyric AcidVesicular Inhibitory Amino Acid Transport ProteinsViaat protein, mouseEEGparadoxical sleepREM sleepslow wave sleepthetawaking

Identifiers

PMID32576622
PMCPMC7392501
OpenAlexW3049588971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.