Evidence map›Paper›PMID 32576621›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

NPY/NPF-Related Neuropeptide FLP-34 Signals from Serotonergic Neurons to Modulate Aversive Olfactory Learning in

Melissa Fadda, Nathan De Fruyt, Charline Borghgraef, Jan Watteyne, Katleen Peymen, Elke Vandewyer, Francisco J Naranjo Galindo, Amanda Kieswetter, Olivier Mirabeau, Yee Lian Chew and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Hungry for Knowledge: Octopamine Signaling Regulates Hunger-Enhanced Olfactory Learning.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Frontiers in aging neuroscience · 2026
    Review
  5. Article
  6. Article
  7. Serotonin-Mediated Avoidance and Immune Suppression inBiochemistry research international · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Behavioral Tests for Associative Learning in Caenorhabditis elegans.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  15. Article
  16. Article
  17. A molecular atlas of adultbioRxiv : the preprint server for biology · 2023
    Article
  18. Review
  19. A serotonergic circuit regulates aversive associative learning under mitochondrial stress inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Melissa FaddaDepartment of Biology, KU Leuven, Leuven, 3000, Belgium.
Nathan De FruytDepartment of Biology, KU Leuven, Leuven, 3000, Belgium.
Charline BorghgraefDepartment of Biology, KU Leuven, Leuven, 3000, Belgium.
Jan WatteyneDepartment of Biology, KU Leuven, Leuven, 3000, Belgium.
Katleen PeymenDepartment of Biology, KU Leuven, Leuven, 3000, Belgium.
Elke VandewyerDepartment of Biology, KU Leuven, Leuven, 3000, Belgium.
Francisco J Naranjo GalindoDepartment of Biology, KU Leuven, Leuven, 3000, Belgium.
Amanda KieswetterDepartment of Biology, KU Leuven, Leuven, 3000, Belgium.
Olivier MirabeauGenetics and Biology of Cancers Unit, Institut Curie, Institut National de la Santé et de la Recherche Médicale U830, Paris Sciences et Lettres Research University, Paris, 75005, France.
Yee Lian ChewIllawarra Health & Medical Research Institute School of Chemistry & Molecular Bioscience, University of Wollongong, Wollongong, 2522 New South Wales, Australia.
Isabel BeetsDepartment of Biology, KU Leuven, Leuven, 3000, Belgium liliane.schoofs@kuleuven.be isabel.beets@kuleuven.be.
Liliane SchoofsDepartment of Biology, KU Leuven, Leuven, 3000, Belgium liliane.schoofs@kuleuven.be isabel.beets@kuleuven.be.ORCID 0000-0002-1673-432X
KU Leuven · BEInstitut Curie · FRUniversity of Wollongong · AU

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Aversive learning is fundamental for animals to increase chances of survival. In addition to classical neurotransmitters, neuropeptides have emerged to modulate such complex behaviors. Among them, neuropeptide Y (NPY) is well known to promote aversive memory acquisition in mammals. Here we identify an NPY/neuropeptide F (NPF)-related neuropeptide system in

Indexed as

AnimalsAppetitive BehaviorAssociation LearningAvoidance LearningButanonesCaenorhabditis elegansDiacetylDose-Response Relationship, DrugFemaleGene Expression RegulationLocomotionMaleNeuropeptidesNeuropeptide YSerotonergic NeuronsSmellButanonesDiacetylneuropeptide FNeuropeptidesNeuropeptide Yaversive learningCaenorhabditis elegansGPCRneuropeptide Yserotonin

Identifiers

PMID32576621
PMCPMC7392509
OpenAlexW3037308564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.