ArticleJournal of neurology, neurosurgery, and psychiatry2020
Effects of
Article in Journal of neurology, neurosurgery, and psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Altered brain connectivity in hyperkinetic movement disorders: A review of resting-state fMRI.NeuroImage. Clinical · 2023Pooled it
- Autonomic, Endocrine, and Inflammation Profiles in Functional Neurological Disorder: A Systematic Review and Meta-Analysis.The Journal of neuropsychiatry and clinical neurosciences · 2022Pooled it
- Imaging biomarkers in functional neurological disorders.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Review
- Exploring the Dynamic Relationship Between Migraine and Functional Neurological Disorders: A Narrative Review.Current pain and headache reports · 2026Review
- Mark Hallett and the renaissance of functional neurological disorder.Clinical parkinsonism & related disorders · 2026Review
- Successful Treatment of Functional Neurologic Symptom Disorder (Conversion Disorder) With Subdissociative Dose Ketamine in the Emergency Department.Journal of the American College of Emergency Physicians open · 2025Article
- Genome-wide study of somatic symptom and related disorders identifies novel genomic loci and map genetic architecture.medRxiv : the preprint server for health sciences · 2025Article
- Iatrogenic harm in functional neurological disorder.Brain : a journal of neurology · 2025Review
- Predictive Processing and the Pathophysiology of Functional Neurological Disorder.Current topics in behavioral neurosciences · 2025Review
- Migraine and functional neurological disorder (FND)-a review of comorbidity and potential overlap.Brain communications · 2025Review
- Orthodontic considerations for managing patients with functional movement disorders: a narrative review and clinical guide.Frontiers in dental medicine · 2025Review
- Salivary oxytocin and amygdalar alterations in functional neurological disorders.Brain communications · 2025Article
- Functional Neurologic Disorder,Neurology · 2024Article
- Biomarkers and Rehabilitation for Functional Neurological Disorder.Journal of personalized medicine · 2024Review
- Functional Movement Disorders: Updates and Clinical Overview.Journal of movement disorders · 2024Article
- Healthcare employment as a risk factor for functional neurological disorder: A case-control study.European journal of neurology · 2024Article
- Polymorphism of glucocorticoid receptor gene (rs41423247) in functional seizures (psychogenic nonepileptic seizures/attacks).Epilepsia open · 2023Article
- Increased Frequency of Self-Reported Obsessive-Compulsive Symptoms in Patients with Functional Movement Disorders.Movement disorders clinical practice · 2023Article
- Article
- Methylome changes associated with functional movement/conversion disorder: Influence of biological sex and childhood abuse exposure.Progress in neuro-psychopharmacology & biological psychiatry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundFunctional movement disorders (FMDs), part of the wide spectrum of functional neurological disorders (conversion disorders), are common and often associated with a poor prognosis. Nevertheless, little is known about their neurobiological underpinnings, particularly with regard to the contribution of genetic factors. Because FMD and stress-related disorders share a common core of biobehavioural manifestations, we investigated whether variants in stress-related genes also contributed, directly and interactively with childhood trauma, to the clinical and circuit-level phenotypes of FMD.
methodsSixty-nine patients with a 'clinically defined' diagnosis of FMD were genotyped for 18 single-nucleotide polymorphisms (SNPs) from 14 candidate genes. FMD clinical characteristics, psychiatric comorbidity and symptomatology, and childhood trauma exposure were assessed. Resting-state functional connectivity data were obtained in a subgroup of 38 patients with FMD and 38 age-matched and sex-matched healthy controls. Amygdala-frontal connectivity was analysed using a whole-brain seed-based approach.
resultsAmong the SNPs analysed, a tryptophan hydroxylase 2 (
conclusionsThis is, to our knowledge, the first study showing that the
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.