ArticleBMJ open respiratory research2020
ILD-specific health-related quality of life in systemic sclerosis-associated ILD compared with IPF.
Article in BMJ open respiratory research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- ERS/EULAR clinical practice guidelines for connective tissue disease-associated interstitial lung disease.The European respiratory journal · 2026Guideline
- Health-related quality of life and health state utility value in idiopathic pulmonary fibrosis: a systematic review and meta-analysis.Health and quality of life outcomes · 2025Pooled it
- Lung ultrasound B-line quantification in CTD-ILD: a cross-sectional single-center observational study.Scientific reports · 2026Observational
- Quality of life in patients with hypersensitivity pneumonitis and with idiopathic pulmonary fibrosis in real-life clinical practice.Journal of thoracic disease · 2025Article
- Association of Health-Related Quality of Life with Functional and Radiological Outcomes in Patients with Rheumatoid Arthritis-Associated Interstitial Lung Disease, Systemic Sclerosis-Associated Interstitial Lung Disease, and Idiopathic Pulmonary Fibrosis.Archives of rheumatology · 2025Article
- Association of tracheal diameter with respiratory function and fibrosis severity in idiopathic pulmonary fibrosis patients.BMC pulmonary medicine · 2025Article
- Clinical characteristics and survival of pulmonary arterial hypertension with or without interstitial lung disease in systemic sclerosis.Arthritis research & therapy · 2023Article
- Home-Based Spirometry in Patients with Interstitial Lung Diseases: A Real-Life Pilot "FACT" Study from Serbia.Journal of personalized medicine · 2023Article
- Clinical trial simulations in pulmonary fibrosis: patient-focused insights and adaptations.ERJ open research · 2023Article
- Comparison of different reference values for lung function: implications of inconsistent use among centers.BMC pulmonary medicine · 2023Article
- Health-related quality of life in a multiracial Asian interstitial lung disease cohort.Journal of thoracic disease · 2022Article
- Patient preferences for the treatment of systemic sclerosis-associated interstitial lung disease: a discrete choice experiment.Rheumatology (Oxford, England) · 2022Article
- Quality of life in SSc-ILD patients: Understanding the impact of the ILD and the needs of the SSc-ILD patients and their need for caregivers in France.Journal of scleroderma and related disorders · 2022Article
- Use of ultrasound to diagnose and monitor interstitial lung disease in rheumatic diseases.Clinical rheumatology · 2021Review
- Web-Based COPD Risk Self-Assessment Identifies a High-Risk Group With HRQoL Resembling Self-Reported COPD: Cross-Sectional Survey.Inquiry : a journal of medical care organization, provision and financingArticle
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIdiopathic pulmonary fibrosis (IPF) and systemic sclerosis-associated interstitial lung disease (SSc-ILD) are fibrotic ILDs with divergent disease populations. Little is known about health-related quality of life (HRQL) in SSc-ILD relative to IPF.
methodsWe used the Kings Brief Interstitial Lung Disease Questionnaire (K-BILD) to compare HRQL in a cross-sectional study of 57 patients with IPF and 29 patients with SSc-ILD. Analysis of covariance was used to adjust for age, gender and lung function.
resultsThe unadjusted mean K-BILD score was 63.1 (95% CI 57.1 to 69.1) among patients with SSc-ILD, as compared with 54.7 (51.8-57.5) among those with IPF (p=0.005). However, this difference in HRQL was attenuated after adjustment for age, gender and lung function. In a multivariable model, only forced vital capacity was associated with K-BILD scores. K-BILD scores were correlated with both forced vital capacity and with other relevant HRQL measures, regardless of ILD diagnosis. DISCUSSION: Patients with SSc-ILD may have better ILD-specific quality of life than patients with IPF, but this difference appears to be driven primarily by better lung function. These results underscore the impact of lung function on HRQL in fibrotic ILD and the utility of K-BILD to assess HRQL in SSc-ILD.
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