Evidence map›Paper›PMID 32576497›Full record

Observational studyThe journal of sexual medicine2020

Evaluating the Impact of Penile Girth Discrepancy on Patient Bother in Men With Peyronie's Disease: An Observational Study.

Carolyn A Salter, Bruno Nascimento, Jean-Etienne Terrier, Hisanori Taniguchi, Helen Bernie, Eduardo Miranda, Lawrence Jenkins, Elizabeth Schofield, John P Mulhall

Abstract readObservational Study
In one paragraph

Observational study in The journal of sexual medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carolyn A SalterDepartment of Urology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Bruno NascimentoDepartment of Urology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Jean-Etienne TerrierDepartment of Urology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Hisanori TaniguchiDepartment of Urology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Helen BernieDepartment of Urology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Eduardo MirandaDepartment of Urology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Lawrence JenkinsDepartment of Urology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Elizabeth SchofieldDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
John P MulhallDepartment of Urology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: mulhalj1@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Elisa de Stanchina · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundMen with Peyronie's disease (PD) may experience penile narrowing. Little data on penile girth changes and their psychosocial impact exist.

aimTo assess girth discrepancy in men with PD and its association with patient bother.

methodsThis was a retrospective observational study. All patients with PD at our institution who were seen in the sexual medicine clinic and who completed 3 validated instruments the PD questionnaire (PDQ), Self-Esteem and Relationship (SEAR) questionnaire, and a depression questionnaire, the Center for Epidemiologic Studies Depression Scale (CES-D), and a curvature assessment were included. Patient and PD characteristics are described. Associations of instability and bother to girth differences are assessed. 2 outcomes for girth differences are classified as (i) girth difference of ≥ 1 cm vs less and (ii) girth differences of ≥10% vs less. Unadjusted and adjusted effects of PD and patient characteristics are assessed on the outcome of high bother using logistic regression models. OUTCOMES: The main outcomes of this study were penile girth changes, instability, and questionnaire scores. High bother was defined as a PDQ bother score of ≥9.

resultsA total of131 men had midshaft curvature and were the focus of the study. Their mean age was 59 ± 9 (range 31-78) years. PD duration was 16 ± 25 (range 1-180) months, with a mean degree of primary curvature of 37 ± 20 CLINICAL IMPLICATIONS: Penile girth changes have little impact on overall psychosocial well-being. The degree of penile curvature is the primary predictor of patient bother. STRENGTHS AND LIMITATIONS: Strengths include a large patient population and use of validated questionnaires. Limitations include single-center, retrospective study and subjective instability grading.

conclusionsPenile girth discrepancy in men with PD has limited psychosocial impact. Clinically significant bother was associated with the degree of primary curvature. Salter CA, Nascimento B, Terrier, JE, et al. Evaluating the Impact of Penile Girth Discrepancy on Patient Bother in Men With Peyronie's Disease: An Observational Study. J Sex Med 2020;17:1560-1565.

Indexed as

Penile IndurationAdultAgedHumansMaleMiddle AgedPenisRetrospective StudiesSurveys and QuestionnairesTreatment OutcomePatient BotherPenile GirthPenile InstabilityPeyronie's DiseasePsychosocial Impact

Identifiers

PMID32576497
PMCPMC8519166

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.