Evidence map›Paper›PMID 32576150›Full record

ArticleBMC neurology2020

Pre-stroke adherence to a Mediterranean diet pattern is associated with lower acute ischemic stroke severity: a cross-sectional analysis of a prospective hospital-register study.

Pablo M Lavados, Enrico Mazzon, Alexis Rojo, Alejandro M Brunser, Verónica V Olavarría

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In one paragraph

Article in BMC neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Mediterranean Lifestyle to Promote Physical, Mental, and Environmental Health: The Case of Chile.International journal of environmental research and public health · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pablo M LavadosDepartamento de Neurología y Psiquiatría, Clínica Alemana de Santiago, Facultad de Medicina, Clínica Alemana Universidad del Desarrollo, Unidad de Neurología Vascular, Servicio de Neurología, Santiago, Chile.
Enrico MazzonDepartamento de Neurología y Psiquiatría y Departamento de Paciente Critico, Clínica Alemana de Santiago, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Unidad de Neurología Vascular, Servicio de Neurología, Avenida Vitacura 5951, Vitacura, 7650568, Santiago, Chile.
Alexis RojoServicio de Neurología, Hospital Clínico Herminda Martin de Chillán, Servicio de Salud Ñuble, Chillán, Chile.
Alejandro M BrunserDepartamento de Neurología y Psiquiatría y Departamento de Urgencia, Clínica Alemana de Santiago, Facultad de Medicina, Universidad del Desarrollo, Clínica Alemana, Unidad de Neurología Vascular, Servicio de Neurología, Santiago, Chile.
Verónica V OlavarríaDepartamento de Neurología y Psiquiatría y Departamento de Paciente Critico, Clínica Alemana de Santiago, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Unidad de Neurología Vascular, Servicio de Neurología, Avenida Vitacura 5951, Vitacura, 7650568, Santiago, Chile. veroolavarria@yahoo.com.ORCID http://orcid.org/0000-0003-4300-9921

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh adherence to a Mediterranean Diet is associated with reduced incidence and mortality of acute ischemic stroke (AIS) but may also be associated with severity. Our purpose was to investigate the association of adherence to a Mediterranean diet and severity in a prospective hospital register of AIS patients.

methodsWe included AIS patients admitted from February 2017 to July 2019. All were assessed by a neurologist with a standard stroke protocol, including NIHSS. Adherence to Mediterranean diet was prospectively measured by the 14-point Mediterranean Diet Adherence Screener (MEDAS) and defined as low (0-6 points) or high (7-14 points). Demographic and clinical characteristics were compared by group with univariate analysis. A Generalized Linear Model (GLM) was used to investigate the association of admission NIHSS as a continuous ordinal variable and an ordinal logistic regression (OLR) analysis to determine the independent association of the NIHSS quartiles with adherence to Mediterranean diet.

resultsThree hundred sixty-eight patients were included, mean age 68.3 (17.7), 158 (42.9%) females. The median NIHSS score was 3 (IQR 1-9) and the median MEDAS score was 6 (IQR 4.5-8). Patients with high MEDAS scores had significantly lower; admission NIHSS scores, sedentary lifestyle, body mass index, total and LDL cholesterol levels, but higher alcohol consumption. After adjustments, high adherence to Mediterranean diet remained independently associated with lower stroke severity both in the GLM (β coefficient = - 0.19, p = 0.01) and in the OLR model (OR for lower NIHSS quartiles 0.6 (95% CI 0.37-0.98, p = 0.04).

conclusionsHigher pre-stroke adherence to a Mediterranean diet is independently associated with lower AIS severity.

Indexed as

Diet, MediterraneanStrokeAgedCross-Sectional StudiesFemaleHumansLogistic ModelsMaleMiddle AgedProspective StudiesSeverity of Illness IndexAcute strokeAdherenceIschemic strokeMediterranean dietSeverity

Identifiers

PMID32576150
PMCPMC7310482

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.