Observational studyUnited European gastroenterology journal2020
Endoscopic ultrasound-based multimodal evaluation of the pancreas in patients with suspected early chronic pancreatitis.
Observational study in United European gastroenterology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ultrasound Elastography in Inflammatory Bowel Diseases: A Systematic Review of Accuracy Compared with Histopathological Assessment.Journal of Crohn's & colitis · 2022Pooled it
- Advancing the Diagnosis and Treatment of Early Chronic Pancreatitis Through Innovation in Imaging and Biomarker Profiling-A Narrative Review.Life (Basel, Switzerland) · 2025Review
- The Role of Endoscopic Ultrasound in Early Chronic Pancreatitis.Diagnostics (Basel, Switzerland) · 2024Review
- The Latest Advancements in Diagnostic Role of Endosonography of Pancreatic Lesions.Journal of clinical medicine · 2023Review
- Endoscopic Ultrasound (EUS) Guided Elastography.Diagnostics (Basel, Switzerland) · 2023Review
- Nutritional Support in Pancreatic Diseases.Nutrients · 2022Review
- Usefulness of endoscopic ultrasound in children with pancreatobiliary and gastrointestinal symptoms.Endoscopy international open · 2022Article
- UEGWeek: The modern School of Athens.United European gastroenterology journal · 2021Article
- Comprehensive review of diagnostic modalities for early chronic pancreatitis.World journal of gastroenterology · 2021Review
- Pancreatic Fibrosis (Early Chronic Pancreatitis) as Emerging Diagnosis in Structural Causes of Dyspepsia: Evidence from Endoscopic Ultrasonography and Shear Wave Elastography.Diagnostics (Basel, Switzerland) · 2021Article
- Multimodal MRI Analysis of Brain Metabolism in Maintenance Hemodialysis Patients Based on Cognitive Computing.Journal of healthcare engineering · 2021Article
- Early chronic pancreatitis: a challenge not so far to be met.United European gastroenterology journal · 2020Article
- The role of EUS in the diagnosis of early chronic pancreatitis.Endoscopic ultrasoundArticle
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8 authors.
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Abstract
backgroundDiagnosis of early chronic pancreatitis is a clinical challenge and hindered by the lack of a gold standard. Endoscopic ultrasound (EUS) and the endoscopic pancreatic function test (ePFT) are the most sensitive morphological and functional methods in this setting. EUS-elastography allows for the quantification (strain ratio) of pancreatic fibrosis, and the dynamic evaluation of the main pancreatic duct compliance provides additional information. We developed a multimodal EUS-based approach for the evaluation of the pancreas by integrating these four methods in a single procedure.
objectiveWe aim to describe morphological and functional pancreatic abnormalities in patients with clinical suspicion of chronic pancreatitis and inconclusive EUS findings by using the multimodal EUS-based approach.
methodsThis was a prospective, cross-sectional, observational study of patients with clinically suspected chronic pancreatitis and indeterminate EUS criteria of the disease. EUS criteria of chronic pancreatitis, quantitative pancreatic elastography, ePFT and compliance of the main pancreatic duct were evaluated in a single procedure.
resultsIn total, 53 patients with 3-4 EUS criteria of chronic pancreatitis were included (mean age 39.7 years, 29 male). Strain ratio was abnormally high in all patients. Peak bicarbonate concentration was decreased in 43 patients (81.1%) and the main pancreatic duct compliance was reduced in 41 patients (77.3%). Some 34 patients (64.1%) had abnormal results at EUS, elastography, ePFT and compliance of the main pancreatic duct.
conclusionsA multimodal EUS-based test for the morphological and functional evaluation of the pancreas is presented, which allows detecting mild pancreatic abnormalities in patients with suspected early chronic pancreatitis. The presence of abnormal morphological and functional evaluation of the pancreas could support the clinical suspicion of early chronic pancreatitis in the appropriate clinical setting.
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