Evidence map›Paper›PMID 32575869›Full record

ArticleJournal of clinical medicine2020

Genetic Variation in CCL18 Gene Influences CCL18 Expression and Correlates with Survival in Idiopathic Pulmonary Fibrosis: Part A.

Ivo A Wiertz, Sofia A Moll, Benjamin Seeliger, Nicole P Barlo, Joanne J van der Vis, Nicoline M Korthagen, Ger T Rijkers, Henk J T Ruven, Jan C Grutters, Antje Prasse and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Observational
  7. Immunobiology of pulmonary fibrosis.Frontiers in immunology · 2025
    Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Towards Treatable Traits for Pulmonary Fibrosis.Journal of personalized medicine · 2022
    Review
  20. Multiplatform Single-Cell Analysis Identifies Immune Cell Types Enhanced in Pulmonary Fibrosis.American journal of respiratory cell and molecular biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ivo A WiertzCentre for Interstitial Lung Diseases, Department of Pulmonology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.
Sofia A MollCentre for Interstitial Lung Diseases, Department of Pulmonology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.
Benjamin SeeligerDepartment of Respiratory Medicine, Hannover Medical School and Biomedical Research in End-stage and Obstructive Lung Disease Hannover, German Lung Research Center (DZL), 30265 Hannover, Germany.ORCID 0000-0001-7373-752X
Nicole P BarloCentre for Interstitial Lung Diseases, Department of Pulmonology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.
Joanne J van der VisDepartment of Medical Microbiology and Immunology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.ORCID 0000-0002-6727-8416
Nicoline M KorthagenCentre for Interstitial Lung Diseases, Department of Pulmonology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.
Ger T RijkersDepartment of Medical Microbiology and Immunology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.
Henk J T RuvenDepartment of Clinical Chemistry, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.
Jan C GruttersCentre for Interstitial Lung Diseases, Department of Pulmonology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.
Antje PrasseDepartment of Respiratory Medicine, Hannover Medical School and Biomedical Research in End-stage and Obstructive Lung Disease Hannover, German Lung Research Center (DZL), 30265 Hannover, Germany.
Coline H M van MoorselCentre for Interstitial Lung Diseases, Department of Pulmonology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.
St. Antonius Ziekenhuis · NLMedizinische Hochschule Hannover · DEUniversity Medical Center Utrecht · NL

Funding

ZonMW TopZorg St Antonius research grant 842002003ZonMW TRopZorg St. Antonius Care Grant 842002001
6 · The paper itself

Abstract

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic disease, characterized by fibroblast proliferation and extracellular matrix deposition. CC-chemokine ligand 18 (CCL18) upregulates the production of collagen by lung fibroblasts and is associated with mortality. This study was designed to evaluate the influence of single nucleotide polymorphisms (SNPs) in the

Indexed as

CCL18chemokineidiopathic pulmonary fibrosissingle nucleotide polymorphismsurvival

Identifiers

PMID32575869
PMCPMC7356165
OpenAlexW4233920241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.