Evidence map›Paper›PMID 32575844›Full record

ArticleCells2020

The Anti-Inflammatory and Pain-Relieving Effects of AR170, an Adenosine A

Luca Antonioli, Elena Lucarini, Catia Lambertucci, Matteo Fornai, Carolina Pellegrini, Laura Benvenuti, Lorenzo Di Cesare Mannelli, Andrea Spinaci, Gabriella Marucci, Corrado Blandizzi and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. 2-Substituted (N)-Methanocarba AACS pharmacology & translational science · 2024
    Article
  4. Adenosine-mediated immune responses in inflammatory bowel disease.Frontiers in cell and developmental biology · 2024
    Review
  5. Article
  6. First Potent Macrocyclic AACS pharmacology & translational science · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Selective AACS medicinal chemistry letters · 2022
    Article
  11. Review
  12. AEuropean journal of medicinal chemistry · 2022
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Luca AntonioliDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0003-1241-617X
Elena LucariniDepartment of Neurosciences, Psychology, Drug Research and Child Health-Neurofarba-Section of Pharmacology and Toxicology, University of Florence, 50139 Florence, Italy.ORCID 0000-0002-3459-2660
Catia LambertucciSchool of Pharmacy, Medicinal Chemistry Unit, University of Camerino, 62032 Camerino (MC), Italy.ORCID 0000-0003-2004-1531
Matteo FornaiDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Carolina PellegriniDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.
Laura BenvenutiDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Lorenzo Di Cesare MannelliDepartment of Neurosciences, Psychology, Drug Research and Child Health-Neurofarba-Section of Pharmacology and Toxicology, University of Florence, 50139 Florence, Italy.ORCID 0000-0001-8374-4432
Andrea SpinaciSchool of Pharmacy, Medicinal Chemistry Unit, University of Camerino, 62032 Camerino (MC), Italy.
Gabriella MarucciSchool of Pharmacy, Medicinal Chemistry Unit, University of Camerino, 62032 Camerino (MC), Italy.
Corrado BlandizziDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Carla GhelardiniDepartment of Neurosciences, Psychology, Drug Research and Child Health-Neurofarba-Section of Pharmacology and Toxicology, University of Florence, 50139 Florence, Italy.
Rosaria VolpiniSchool of Pharmacy, Medicinal Chemistry Unit, University of Camerino, 62032 Camerino (MC), Italy.ORCID 0000-0002-5304-5232
Diego Dal BenSchool of Pharmacy, Medicinal Chemistry Unit, University of Camerino, 62032 Camerino (MC), Italy.ORCID 0000-0002-6616-6885
Università di Camerino · ITUniversity of Pisa · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pharmacological activation of A

Indexed as

AnimalsAnti-Inflammatory AgentsColitisDisease Models, AnimalHumansMalePurinergic P1 Receptor AgonistsRatsRats, Sprague-DawleyAnti-Inflammatory AgentsPurinergic P1 Receptor AgonistsA3 adenosine receptorsDNBSexperimental colitisimmune cellsoxidative stressvisceral pain

Identifiers

PMID32575844
PMCPMC7348903
OpenAlexW3036603930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.