Porous Graphene Oxide Decorated Ion Selective Electrode for Observing Across-Cytomembrane Ion Transport.

Shihui Hu, Rong Zhang, Yunfang Jia

Open access · goldAbstract readLetter

In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.5field-weighted citation impact, top 37% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shihui HuCollege of Electronic Information and Optical Engineering, Nankai University, Tianjin 300071, China.

Rong ZhangCollege of Electronic Information and Optical Engineering, Nankai University, Tianjin 300071, China.

Yunfang JiaCollege of Electronic Information and Optical Engineering, Nankai University, Tianjin 300071, China.ORCID 0000-0002-2093-2118

Nankai University · CN

Funding

National Natural Science Foundation of China 61771260

6 · The paper itself

Abstract

The technology for measuring cytomembrane ion transport is one of the necessities in modern biomedical research due to its significance in the cellular physiology, the requirements for the non-invasive and easy-to-operate devices have driven lots of efforts to explore the potential electrochemical sensors. Herein, we would like to evidence the exploitation of the porous graphene oxide (PGO) decorated ion selective electrode (ISE) as a detector to capture the signal of cytomembrane ion transport. The tumor cells (MDAMB231, A549 and HeLa) treated by iodide uptake operation, with and without the sodium-iodide-symporter (NIS) expression, are used as proofs of concept. It is found that under the same optimized experimental conditions, the changed output voltages of ISEs before and after the cells' immobilization are in close relation with the NIS related ion's across-membrane transportation, including I

Indexed as

GraphiteIon-Selective ElectrodesIon TransportCell Line, TumorCell MembraneHumansPorositygraphene oxideGraphiteinterfacial micro-environmention selective electrodeion transportporous graphene oxidesodium iodide symporter

Identifiers

PMID32575810

DOI10.3390/s20123500

PMCPMC7349088

OpenAlexW3036637706

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.