ArticleDiagnostics (Basel, Switzerland)2020
Evaluation of BDNF as a Biomarker for Impulsivity in a Psychiatric Population.
Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Inflammation and nitro-oxidative stress in current suicidal attempts and current suicidal ideation: a systematic review and meta-analysis.Molecular psychiatry · 2022Pooled it
- Prenatal opioid exposure alters pain perception and increases long-term health risks in infants with neonatal opioid withdrawal syndrome.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- rTMS Modulation of Behavioral and Biological Measures in 3xTg-AD Mice.Brain sciences · 2024Article
- Peripheral Brain-Derived Neurotrophic Factor (BDNF) and Its Regulatory miRNAs as Biological Correlates of Impulsivity in Young Adults.Metabolites · 2024Article
- Study on correlations of BDNF, PI3K, AKT and CREB levels with depressive emotion and impulsive behaviors in drug-naïve patients with first-episode schizophrenia.BMC psychiatry · 2023Article
- Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Impulsivity is an important risk factor for suicide and therefore, identifying biomarkers associated with impulsivity could be important in evaluating psychiatric patients. Currently, assessment of impulsivity is based solely on clinical evaluation. In this study, brain-derived neurotrophic factor (BDNF), a nerve growth factor, was evaluated as a potential biomarker for impulsivity. We hypothesize that elevated BDNF may result in aberrantly high neurobiological activation, promoting impulsive behaviours. A total of 343 participants were recruited for the study and were divided into two groups, (i) elevated suicide risk (participants admitted to hospital with a recent suicide attempt), and (ii) average suicide risk (non-psychiatric participants and psychiatric participants without a history of suicide attempts). Impulsivity was measured by the Barratt Impulsiveness Scale, and serum BDNF levels were obtained. A regression analysis was performed to identify associations between BDNF and impulsivity. We identified a subtle but significant positive association between BDNF and impulsivity in the average risk for suicide group (B = 0.189,
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