Evidence map›Paper›PMID 32575575›Full record

ReviewInternational journal of molecular sciences2020

Preimplantation Genetic Testing: Where We Are Today.

Ermanno Greco, Katarzyna Litwicka, Maria Giulia Minasi, Elisabetta Cursio, Pier Francesco Greco, Paolo Barillari

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Decision-making criteria in polygenic embryo screening: A survey of reproductive medicine physicians.Genetics in medicine : official journal of the American College of Medical Genetics · 2026
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  13. Structural rearrangements affect blastocyst development.Archives of gynecology and obstetrics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ermanno GrecoReproductive Medicine, Villa Mafalda, 00199 Rome, Italy.
Katarzyna LitwickaReproductive Medicine, Villa Mafalda, 00199 Rome, Italy.
Maria Giulia MinasiReproductive Medicine, Villa Mafalda, 00199 Rome, Italy.ORCID 0000-0003-3624-6961
Elisabetta CursioReproductive Medicine, Villa Mafalda, 00199 Rome, Italy.
Pier Francesco GrecoReproductive Medicine, Villa Mafalda, 00199 Rome, Italy.
Paolo BarillariReproductive Medicine, Villa Mafalda, 00199 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreimplantation genetic testing (PGT) is widely used today in in-vitro fertilization (IVF) centers over the world for selecting euploid embryos for transfer and to improve clinical outcomes in terms of embryo implantation, clinical pregnancy, and live birth rates.

methodsWe report the current knowledge concerning these procedures and the results from different clinical indications in which PGT is commonly applied.

resultsThis paper illustrates different molecular techniques used for this purpose and the clinical significance of the different oocyte and embryo stage (polar bodies, cleavage embryo, and blastocyst) at which it is possible to perform sampling biopsies for PGT. Finally, genetic origin and clinical significance of embryo mosaicism are illustrated.

conclusionsThe preimplantation genetic testing is a valid technique to evaluated embryo euploidy and mosaicism before transfer.

Indexed as

FemaleFertilization in VitroGenetic TestingHumansMosaicismPloidiesPregnancyPreimplantation Diagnosisbiopsyendometriumeuploid embryoimplantationin-vitro fertilizationmosaicismpregnancypreimplantation genetic screening

Identifiers

PMID32575575
PMCPMC7352684

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.