Evidence map›Paper›PMID 32575506›Full record

ArticleInternational journal of molecular sciences2020

SSADH Variants Increase Susceptibility of U87 Cells to Mitochondrial Pro-Oxidant Insult.

Giovanna Menduti, Alessandra Vitaliti, Concetta Rosa Capo, Daniele Lettieri-Barbato, Katia Aquilano, Patrizia Malaspina, Luisa Rossi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Giovanna MendutiDepartment of Biology, University of Rome Tor Vergata, 00133 Rome, Italy.
Alessandra VitalitiDepartment of Biology, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0001-9394-8674
Concetta Rosa CapoDepartment of Biology, University of Rome Tor Vergata, 00133 Rome, Italy.
Daniele Lettieri-BarbatoDepartment of Biology, University of Rome Tor Vergata, 00133 Rome, Italy.
Katia AquilanoDepartment of Biology, University of Rome Tor Vergata, 00133 Rome, Italy.
Patrizia MalaspinaDepartment of Biology, University of Rome Tor Vergata, 00133 Rome, Italy.
Luisa RossiDepartment of Biology, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0001-8668-6370
University of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Succinate semialdehyde dehydrogenase (SSADH) is a mitochondrial enzyme, encoded by

Indexed as

Polymorphism, Single NucleotideAmino Acid SubstitutionCell Line, TumorDown-RegulationHumansLipid PeroxidationMitochondriaParaquatProtein Sorting SignalsProteolysisSuccinate-Semialdehyde DehydrogenaseALDH5A1 protein, humanParaquatProtein Sorting SignalsSuccinate-Semialdehyde Dehydrogenase4-HNEALDH5A1GABAmitochondriaparaquatSSASSADHU87 cells

Identifiers

PMID32575506
PMCPMC7352567
OpenAlexW3036318127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.