ArticleCells2020
Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT) beyond
Open access · goldAbstract read
In one paragraph
Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 59 citations in OpenAlex.
- A phase II basket trial of dual anti-CTLA-4 and anti-PD-1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort.Cancer communications (London, England) · 2025Trial
- Pregnancy-Associated Small Cell Carcinoma of the Ovary, Hypercalcaemic Type Initially Misdiagnosed as Granulosa Cell Tumour: Diagnostic Pitfalls, Treatment Challenges, and Molecular Confirmation by Next-Generation Sequencing.Cancer reports (Hoboken, N.J.) · 2026Article
- Clinicopathological and molecular characteristics of small cell carcinoma of the ovary, hypercalcemic type: three case reports.Discover oncology · 2026Article
- Long-term remission after multimodal therapy in metastatic small cell carcinoma of the ovary, hypercalcemic type: A case report.Gynecologic oncology reports · 2026Article
- Case Report: Whole genome sequencing of small cell ovarian carcinomas.Frontiers in oncology · 2026Article
- Epigenetic reprogramming as the nexus of cancer stemness and therapy resistance: implications for biomarker discovery.Discover oncology · 2025Review
- Loss of SMARCA4 Leads to Intron Retention and Generation of Tumor-Associated Antigens in Small Cell Carcinoma of the Ovary, Hypercalcemic Type.Cancer research · 2025Article
- MYC Regulates a DNA Repair Gene Expression Program in Small Cell Carcinoma of the Ovary, Hypercalcemic Type.Cancers · 2025Article
- Single-cell RNA sequencing reveals the intra-tumoral heterogeneity and immune microenvironment of small cell carcinoma of the ovary, hypercalcemic type.Journal of ovarian research · 2025Article
- Organoid drug profiling identifies methotrexate as a therapy for SCCOHT, a rare pediatric cancer.Science advances · 2025Article
- Tumor-agnostic therapy: a potential therapeutic approach for SMARCA4-deficient malignancies.Therapeutic advances in medical oncology · 2025Review
- Small cell carcinoma of the ovary, hypercalcemic type: a mini review.Frontiers in oncology · 2025Review
- When rarity meets thoracic cancers: a narrative review from ITMIG 2024.Mediastinum (Hong Kong, China) · 2025Review
- Chromatin remodeling complexes: architects influencing breast cancer progression.Frontiers in cell and developmental biology · 2025Review
- SMARCA4-deficient uterine tumors in young women: response to immune checkpoint inhibitors.International cancer conference journal · 2024Article
- Review
- Relevance of Molecular Pathology for the Diagnosis of Sex Cord-Stromal Tumors of the Ovary: A Narrative Review.Cancers · 2023Review
- Article
- Primary cutaneous SMARCA4-deficient undifferentiated malignant neoplasm: first two cases with clinicopathologic and molecular comparison to eight visceral counterparts.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2022Article
- The Emerging Role of Chromatin Remodeling Complexes in Ovarian Cancer.International journal of molecular sciences · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 6 institutions in 4 countries.
Aurélie AugusteMedical Oncologist, Gynecology Unit, Lead Translational Research Team, INSERM U981, Gustave Roussy, 94805 Villejuif, France.
Félix Blanc-DurandGynecological Unit, Department of Medicine, Gustave Roussy, 94805 Villejuif, France.ORCID 0000-0002-5277-1515
Marc DelogerBioinformatics Core Facility, Gustave Roussy Cancer Center, UMS CNRS 3655/INSERM 23 AMMICA, 94805 Villejuif, France.ORCID 0000-0002-6352-101X
Audrey Le FormalMedical Oncologist, Gynecology Unit, Lead Translational Research Team, INSERM U981, Gustave Roussy, 94805 Villejuif, France.
Rohan BarejaCaryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10001, USA.
David C WilkesCaryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10001, USA.ORCID 0000-0002-2422-1145
Catherine RichonGenomic Platform Gustave Roussy Cancer Institute, 94805 Villejuif, France.
Béatrice BrunnGynecological Unit, Department of Medicine, Gustave Roussy, 94805 Villejuif, France.
Olivier CaronGenomic Platform Gustave Roussy Cancer Institute, 94805 Villejuif, France.
Mojgan Devouassoux-ShisheboranDepartment of Pathology, Hospital de la Croix Rousse, 69000 Lyon, France.
Sébastien GouyGynecological Unit, Department of Medicine, Gustave Roussy, 94805 Villejuif, France.
Philippe MoriceGynecological Unit, Department of Medicine, Gustave Roussy, 94805 Villejuif, France.
Enrica BentivegnaGynecological Unit, Department of Medicine, Gustave Roussy, 94805 Villejuif, France.
Andrea SbonerCaryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10001, USA.
Olivier ElementoCaryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10001, USA.
Mark A RubinDepartment for BioMedical Research, University of Bern, 3001 Bern, Switzerland.ORCID 0000-0002-8321-9950
Patricia PautierGynecological Unit, Department of Medicine, Gustave Roussy, 94805 Villejuif, France.
Catherine GenestieDepartment of Pathology, Gustave Roussy, 94805 Villejuif, France.
Joanna CyrtaCaryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10001, USA.
Alexandra LearyMedical Oncologist, Gynecology Unit, Lead Translational Research Team, INSERM U981, Gustave Roussy, 94805 Villejuif, France.
Institut Gustave Roussy · FRCornell University · USInserm · FRUniversity of Bern · CHCentre National de la Recherche Scientifique · FRHôpital de la Croix-Rousse · FR
Funding
No grant is acknowledged in the PubMed record.
Abstract
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is an aggressive malignancy that occurs in young women, is characterized by recurrent loss-of-function mutations in the
Indexed as
Comparative Genomic HybridizationAntigens, NeoplasmCarcinoma, Small CellCohort StudiesDNA HelicasesFemaleHumansHypercalcemiaMutationNuclear ProteinsOvarian NeoplasmsOvaryTranscription FactorsAntigens, NeoplasmDNA HelicasesNuclear ProteinsSMARCA4 protein, humanTranscription Factorshypercalcemicovarysmall cell carcinomaSMARCA4SWI/SNF
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.