ReviewInternational journal of molecular sciences2020
Dietary Regulation of Memory T Cells.
Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
17 citing papers in PubMed.
- Hormonal rewiring of immunity during dietary restriction ensures host defense and systemic glucose conservation.Immunity · 2026Article
- Sucralose as a Way to Enhance Regulatory T Cells, the SWEET Trial: Clinical Research Protocol.Canadian journal of kidney health and disease · 2026Article
- Mendelian Randomization Mediation Analysis Reveals the Impact of Dietary Preferences on Preeclampsia and Fetal Growth Restriction via Immune Modulation.Food science & nutrition · 2025Article
- Associations between Calcium Intake and T-cell Infiltration in Colorectal Tumors.Cancer prevention research (Philadelphia, Pa.) · 2025Article
- Protein and Aging: Practicalities and Practice.Nutrients · 2025Review
- Unraveling the role of shrimp hydrolysate as a food supplement in the immune function and fecal microbiota of beagle dogs.Scientific reports · 2025Article
- Nutritional Deficiencies and Management in Tuberculosis: Pharmacotherapeutic and Clinical Implications.Nutrients · 2025Review
- Sex-Dependent T Cell Dysregulation in Mice with Diet-Induced Obesity.International journal of molecular sciences · 2024Article
- Nutritional modulation of antitumor immunity.Current opinion in immunology · 2024Review
- Association of dietary patterns with chronic respiratory health among U.S. adults.Frontiers in immunology · 2024Article
- Microbiota configuration determines nutritional immune optimization.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Geriatric nutritional risk index predicts all-cause mortality in the oldest-old patients with acute coronary syndrome: A 10-year cohort study.Frontiers in nutrition · 2023Article
- Drug dosing in children with obesity: a narrative updated review.Italian journal of pediatrics · 2022Review
- Article
- Review
- Obesity, Nutrients and the Immune System in the Era of COVID-19.Nutrients · 2021Review
- The Impact of Obesity and Lifestyle on the Immune System and Susceptibility to Infections Such as COVID-19.Frontiers in nutrition · 2020Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Memory T cells are a fundamental component of immunological memory, providing rapid and potent host protection against secondary challenges. As such, memory T cells are key targets in the design of vaccination strategies and cancer immunotherapies, making it critical to understand the factors and mechanisms that regulate their biology. Diet is an environmental feature that impacts virtually all aspects of host physiology. However, the influence of specific dietary regiments and nutritional components on the immune system is only just starting to be uncovered. This article will review literature regarding the impact of diet and nutrition on memory T cell development, maintenance and function. It was recently shown that caloric restriction without undernutrition enhances memory T cell function, while diets high in fiber are also beneficial. However, memory T cell responses are dysfunctional in extreme nutritional states, such as undernutrition and diet-induced obesity. Therefore, diet and host nutritional status are major regulators of memory T cell biology and host fitness. To define the dietary balance required to promote optimal memory T cell responses could allow for the implementation of rational diet-based therapies that prevent or treat disease. Furthermore, that certain dietary regiments can enhance memory T cell function indicates the possibility of harnessing the underlying mechanisms in the design of novel vaccination strategies and cancer immunotherapies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.