Evidence map›Paper›PMID 32575396›Full record

ArticleBiomolecules2020

Deep Learning of Cancer Stem Cell Morphology Using Conditional Generative Adversarial Networks.

Saori Aida, Junpei Okugawa, Serena Fujisaka, Tomonari Kasai, Hiroyuki Kameda, Tomoyasu Sugiyama

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Machine Learning in Stem Cell Research: From Biological Data to Clinical Translation.Computational and structural biotechnology journal · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Cancer Stem Cells from Definition to Detection and Targeted Drugs.International journal of molecular sciences · 2024
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. CardioVinci: building blocks for virtual cardiac cells using deep learning.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Saori AidaSchool of Computer Science, Tokyo University of Technology, 1401-1 Katakura-machi, Hachioji-shi, Tokyo 192-0982, Japan.
Junpei OkugawaSchool of Bioscience and Technology, Tokyo University of Technology, 1401-1 Katakura-machi, Hachioji-shi, Tokyo 192-0982, Japan.
Serena FujisakaSchool of Bioscience and Technology, Tokyo University of Technology, 1401-1 Katakura-machi, Hachioji-shi, Tokyo 192-0982, Japan.
Tomonari KasaiSchool of Bioscience and Technology, Tokyo University of Technology, 1401-1 Katakura-machi, Hachioji-shi, Tokyo 192-0982, Japan.
Hiroyuki KamedaSchool of Computer Science, Tokyo University of Technology, 1401-1 Katakura-machi, Hachioji-shi, Tokyo 192-0982, Japan.
Tomoyasu SugiyamaSchool of Bioscience and Technology, Tokyo University of Technology, 1401-1 Katakura-machi, Hachioji-shi, Tokyo 192-0982, Japan.
Tokyo University of Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep-learning workflows of microscopic image analysis are sufficient for handling the contextual variations because they employ biological samples and have numerous tasks. The use of well-defined annotated images is important for the workflow. Cancer stem cells (CSCs) are identified by specific cell markers. These CSCs were extensively characterized by the stem cell (SC)-like gene expression and proliferation mechanisms for the development of tumors. In contrast, the morphological characterization remains elusive. This study aims to investigate the segmentation of CSCs in phase contrast imaging using conditional generative adversarial networks (CGAN). Artificial intelligence (AI) was trained using fluorescence images of the

Indexed as

Deep LearningImage Processing, Computer-AssistedAnimalsFemaleGreen Fluorescent ProteinsLung NeoplasmsMiceMice, Inbred BALB CMice, NudeNeoplastic Stem CellsOptical ImagingTumor Cells, CulturedGreen Fluorescent ProteinsCancer stem cellconditional generative adversarial networkgreen fluorescence proteinphase contrasttumor

Identifiers

PMID32575396
PMCPMC7355573
OpenAlexW3036486419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.