ArticleNeuroImage2020
A gradient from long-term memory to novel cognition: Transitions through default mode and executive cortex.
Article in NeuroImage, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- State-dependent signal flow hierarchy in the human cerebral cortex.Nature neuroscience · 2026Article
- Model-based semantic distance reveals adaptive coordination of distinct cognitive systems in flexible knowledge retrieval.Nature communications · 2026Article
- The Neural Processes Underpinning Flexible Semantic Retrieval in Visual and Auditory Modalities.Human brain mapping · 2026Article
- Disrupted cortical organization in schizophrenia based on functional connectivity gradients.European archives of psychiatry and clinical neuroscience · 2026Article
- Differential representations of spatial environments in mPFC and hippocampus underpinning flexible navigation.NeuroImage · 2026Article
- Feature similarity, a sensitive method to capture the functional interaction of brain regions and networks to support flexible behavior.Communications biology · 2025Article
- Functional differentiation and interactions among inferior, medial frontal and posterior temporal cortex in semantic control.Communications biology · 2025Article
- Graded encoding of spatial novelty scales in the human brain.Nature communications · 2025Article
- Whole-Brain Dimensions of Intrinsic Connectivity Capture Modality-Specific and Heteromodal Language Representations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Dynamic and Static Functional Gradient in Temporal Lobe Epilepsy With Hippocampal Sclerosis Versus Healthy Controls.CNS neuroscience & therapeutics · 2025Article
- The Dimensionality of Neural Coding for Cognitive Control Is Gradually Transformed within the Lateral Prefrontal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Self-reports map the landscape of task states derived from brain imaging.Communications psychology · 2025Article
- A double dissociation between semantic and spatial cognition in visual to default network pathways.eLife · 2025Article
- The 7 Muses of Neuro-Creative Cycle: How some patients with Parkinson's disease can unleash latent creativity.AIMS neuroscience · 2025Article
- Divergent and convergent creativity relate to different aspects of semantic control.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Differential reorganization of episodic and semantic memory systems in epilepsy-related mesiotemporal pathology.Brain : a journal of neurology · 2024Article
- Review
- Macroscale brain states support the control of semantic cognition.Communications biology · 2024Article
- A synergistic workspace for human consciousness revealed by Integrated Information Decomposition.eLife · 2024Article
- Creative connections: the neural correlates of semantic relatedness are associated with creativity.Communications biology · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human cognition flexibly guides decision-making in familiar and novel situations. Although these decisions are often treated as dichotomous, in reality, situations are neither completely familiar, nor entirely new. Contemporary accounts of brain organization suggest that neural function is organized along a connectivity gradient from unimodal regions of sensorimotor cortex, through executive regions to transmodal default mode network. We examined whether this graded view of neural organization helps to explain how decision-making changes across situations that vary in their alignment with long-term knowledge. We used a semantic judgment task, which parametrically varied the global semantic similarity of items within a feature matching task to create a 'task gradient', from conceptual combinations that were highly overlapping in long-term memory to trials that only shared the goal-relevant feature. We found the brain's response to the task gradient varied systematically along the connectivity gradient, with the strongest response in default mode network when the probe and target items were highly overlapping conceptually. This graded functional change was seen in multiple brain regions and within individual brains, and was not readily explained by task difficulty. Moreover, the gradient captured the spatial layout of networks involved in semantic processing, providing an organizational principle for controlled semantic cognition across the cortex. In this way, the cortex is organized to support semantic decision-making in both highly familiar and less familiar situations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.