ArticleResuscitation2020
The impact of increased chest compression fraction on survival for out-of-hospital cardiac arrest patients with a non-shockable initial rhythm.
Article in Resuscitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05278923 (The Impact of Soiled Airway Management on CPR Quality), which is not on this map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Impact of Soiled Airway Management on CPR Quality
Who cites it
16 citing papers in PubMed, 44 citations in OpenAlex.
- Prehospital transesophageal echocardiography versus conventional advanced life support in out-of-hospital cardiac arrest (PHTEE-OHCA) - a randomized controlled pilot study.Critical care (London, England) · 2026Trial
- Compromised cardiopulmonary resuscitation quality due to regurgitation during endotracheal intubation: a randomised crossover manikin simulation study.BMC emergency medicine · 2022Trial
- Comparing chest compression quality in 1-min vs. 2-min rescuer rotations with and without audiovisual feedback guidance during full adult advance life support simulated scenarios: a randomized simulation study.Resuscitation plus · 2026Article
- Singapore Advanced Cardiac Life Support Guidelines 2026.Singapore medical journal · 2026Article
- Performance of a novel modified bag-valve-mask ventilation technique during manual ventilation and cardiopulmonary resuscitation: a randomized crossover manikin study.Resuscitation plus · 2026Article
- Performance of the new Laryngeal Tube LTInternational journal of emergency medicine · 2026Article
- Performance metrics in cardiac resuscitation: Rapid cycle deliberate practice (RCDP) versus simulated clinical experience (SCE).Journal of education and health promotion · 2026Article
- Realtime detection of spontaneous circulation in humans during cardiopulmonary resuscitation using a continuous hands-free carotid Doppler: a pilot study.Resuscitation plus · 2025Article
- A hands-free carotid Doppler can identify spontaneous circulation without interrupting cardiopulmonary resuscitation: an animal study.Intensive care medicine experimental · 2024Article
- Bag-Valve-Mask Ventilation and Survival From Out-of-Hospital Cardiac Arrest: A Multicenter Study.Circulation · 2023Article
- Methods for calculating ventilation rates during resuscitation from out-of-hospital cardiac arrest.Resuscitation · 2023Article
- Impact of Ultrasonography on Chest Compression Fraction and Survival in Patients with Out-of-hospital Cardiac Arrest.The western journal of emergency medicine · 2023Article
- Impact of Two Resuscitation Sequences on Alveolar Ventilation during the First Minute of Simulated Pediatric Cardiac Arrest: Randomized Cross-Over Trial.Healthcare (Basel, Switzerland) · 2022Article
- Effect of Early Supraglottic Airway Device Insertion on Chest Compression Fraction during Simulated Out-of-Hospital Cardiac Arrest: Randomised Controlled Trial.Journal of clinical medicine · 2021Article
- Effect on Chest Compression Fraction of Continuous Manual Compressions with Asynchronous Ventilations Using an i-gelHealthcare (Basel, Switzerland) · 2021Article
- Quality of Cardiopulmonary Resuscitation and 5-Year Survival Following in-Hospital Cardiac Arrest.Open access emergency medicine : OAEM · 2021Article
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Authors and funding
21 authors at 14 institutions in 2 countries.
Funding
Abstract
objectiveWe evaluated the effect of chest compression fraction (CCF) on survival to hospital discharge and return of spontaneous circulation (ROSC) in out-of-hospital cardiac arrest (OHCA) patients with non-shockable rhythms.
methodsThis is a retrospective analysis (completed in 2016) of a prospective cohort study which included OHCA patients from ten U.S. and Canadian sites (Resuscitation Outcomes Consortium Epistry and PRIMED study (2007-2011)). We included all OHCA victims of presumed cardiac aetiology, not witnessed by emergency medical services (EMS), without automated external defibrillator shock prior to EMS arrival, receiving > 1 min of CPR with CPR process measures available, and initial non-shockable rhythm. We measured CCF using the first 5 min of electronic CPR records.
resultsDemographics of 12,928 adult patients were: mean age 68; male 59.9%; public location 8.5%; bystander witnessed 35.2%; bystander CPR 39.3%; median interval from 911 to defibrillator turned on 10 min:04 s; initial rhythm asystole 64.8%, PEA 26.0%, other non-shockable 9.2%; compression rate 80-120/min (69.1%); median CCF 74%; ROSC 25.6%; survival to hospital discharge 2.4%. Adjusted odds ratio (OR); 95% confidence intervals (95%CI) of survival for each CCF category were: 0-40% (2.00; 1.16, 3.32); 41-60% (0.83; 0.54, 1.24); 61-80% (1.02; 0.77, 1.35); and 81-100% (reference group). Adjusted (OR; 95%CI) of ROSC for each CCF category were: 0-40% (1.02; 0.79, 1.30); 41-60% (0.83; 0.72, 0.95); 61-80% (0.85; 0.77, 0.94); and 81-100% (reference group).
conclusionsWe observed an incremental benefit from higher CCF on the incidence of ROSC, but not survival, among non-shockable OHCA patients with CCF higher than 40%.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.