Evidence map›Paper›PMID 32574374›Full record

SynthesisInternational journal of cancer2020

Insecticide use and risk of non-Hodgkin lymphoma subtypes: A subset meta-analysis of the North American Pooled Project.

Linda Kachuri, Laura E Beane Freeman, John J Spinelli, Aaron Blair, Manisha Pahwa, Stella Koutros, Shelia Hoar Zahm, Kenneth P Cantor, Dennis D Weisenburger, Punam Pahwa and 4 more

Abstract readMeta-Analysis
In one paragraph

Synthesis in International journal of cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Linda KachuriDepartment of Epidemiology & Biostatistics, University of California San Francisco, San Francisco, California, USA.ORCID 0000-0002-3226-4727
Laura E Beane FreemanDivision of Cancer Epidemiology and Genetics, U.S. National Cancer Institute, Bethesda, Maryland, USA.
John J SpinelliPopulation Oncology, BC Cancer, Vancouver, British Columbia, Canada.
Aaron BlairDivision of Cancer Epidemiology and Genetics, U.S. National Cancer Institute, Bethesda, Maryland, USA.
Manisha PahwaOccupational Cancer Research Centre, Cancer Care Ontario, Toronto, Ontario, Canada.
Stella KoutrosDivision of Cancer Epidemiology and Genetics, U.S. National Cancer Institute, Bethesda, Maryland, USA.ORCID 0000-0001-5294-5485
Shelia Hoar ZahmDivision of Cancer Epidemiology and Genetics, U.S. National Cancer Institute, Bethesda, Maryland, USA.
Kenneth P CantorDivision of Cancer Epidemiology and Genetics, U.S. National Cancer Institute, Bethesda, Maryland, USA.
Dennis D WeisenburgerDepartment of Pathology, City of Hope Medical Center, Duarte, California, USA.
Punam PahwaCanadian Centre for Health and Safety in Agriculture, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
James A DosmanDepartment of Community Health and Epidemiology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
John R McLaughlinDivision of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Paul A DemersOccupational Cancer Research Centre, Cancer Care Ontario, Toronto, Ontario, Canada.
Shelley A HarrisOccupational Cancer Research Centre, Cancer Care Ontario, Toronto, Ontario, Canada.

Funding

Studies of Occupational Cancer (Pesticides)ZIACP010119 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI BEANE FREEMAN, LAURA · 2009 to 2025
$46.1M
STUDIES OF OCCUPATIONAL CANCER--PESTICIDESZ01CP010119 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ALAVANJA, MICHAEL · 1996 to 2008
$5.0M
Intramural NIH HHS Z01 CP010119
6 · The paper itself

Abstract

Insecticide use has been linked to increased risk of non-Hodgkin lymphoma (NHL), however, findings of epidemiologic studies have been inconsistent, particularly for NHL subtypes. We analyzed 1690 NHL cases and 5131 controls in the North American Pooled Project (NAPP) to investigate self-reported insecticide use and risk of NHL overall and by subtypes: follicular lymphoma (FL), diffuse large B-cell lymphoma (DLBCL) and small lymphocytic lymphoma (SLL). Odds ratios (OR) and 95% confidence intervals for each insecticide were estimated using logistic regression. Subtype-specific associations were evaluated using ASSET (Association analysis for SubSETs). Increased risks of multiple NHL subtypes were observed for lindane (OR = 1.60, 1.20-2.10: FL, DLCBL, SLL), chlordane (OR = 1.59, 1.17-2.16: FL, SLL) and DDT (OR = 1.36, 1.06-1.73: DLBCL, SLL). Positive trends were observed, within the subsets with identified associations, for increasing categories of exposure duration for lindane (P

Indexed as

Case-Control StudiesChlordanDDTFemaleHexachlorocyclohexaneHumansInsecticidesLeukemia, Lymphocytic, Chronic, B-CellLogistic ModelsLymphoma, FollicularLymphoma, Large B-Cell, DiffuseMaleSelf ReportUnited StatesChlordanDDTHexachlorocyclohexaneInsecticidesinsecticidesmeta-analysisnon-Hodgkin lymphoma (NHL)organochlorinespesticides

Identifiers

PMID32574374
PMCPMC7689728

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.