Evidence map›Paper›PMID 32574206›Full record

ArticlePloS one2020

Use of antibacterials in the management of symptoms of acute respiratory tract infections among children under five years in Gulu, northern Uganda: Prevalence and determinants.

Hindum Lanyero, Jaran Eriksen, Celestino Obua, Cecilia Stålsby Lundborg, Sarah Nanzigu, Agaba Katureebe, Joan N Kalyango, Moses Ocan

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Review
  7. Journal of public health in Africa · 2025
    Article
  8. Observational
  9. Review
  10. Article
  11. Antibiotic prescription among children with common cold at a district hospital in Uganda.African journal of primary health care & family medicine · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Hindum LanyeroDepartment of Pharmacology and Therapeutics, Makerere University College of Health Sciences, Kampala, Uganda.ORCID 0000-0002-2798-1107
Jaran EriksenDepartment of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0003-1146-5615
Celestino ObuaMbarara University of Science and Technology, Mbarara, Uganda.
Cecilia Stålsby LundborgDepartment of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
Sarah NanziguDepartment of Pharmacology and Therapeutics, Makerere University College of Health Sciences, Kampala, Uganda.
Agaba KatureebeInfectious Diseases Research Collaboration, Kampala, Uganda.
Joan N KalyangoDepartment of Pharmacy, Makerere University College of Health Sciences, Kampala, Uganda.
Moses OcanDepartment of Pharmacology and Therapeutics, Makerere University College of Health Sciences, Kampala, Uganda.
Makerere University · UGInfectious Diseases Research Collaboration · UGKarolinska Institutet · SEKarolinska University Hospital · SEMbarara University of Science and Technology · UG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inappropriate use of antibacterials is a major public health challenge as it can promote emergence of resistance, wastage of financial resources, morbidity and mortality. In this study, we determined the prevalence and factors associated with antibacterial use in managing symptoms of acute respiratory tract infections (ARIs) in households in rural communities of Gulu district, northern Uganda. A cross-sectional study was conducted among households selected using multi-stage sampling. Data were collected through interviews with care-givers of children under five years, using a structured interviewer administered questionnaire. Out of the 856 children who had symptoms of ARIs, 515 (60.2%; CI: 54.5%-65.6%) were treated with antibacterials. The most commonly used antibacterials were amoxicillin (55.2%, n = 358), cotrimoxazole (15.4%, n = 100) and metronidazole (11.4%, n = 74). The determinants of antibacterial use included; getting treatment from a health facility (AOR: 1.85, CI: 1.34-2.56, P < 0.001), households located in peri-urban area (AOR: 2.54, CI: 1.34-4.84, P = 0.005), and a child having cough (AOR: 7.02, CI: 4.36-11.31, P < 0.001). The prevalence of antibacterial use among children under five years with symptoms of ARIs is high in communities of Gulu district, northern Uganda. Getting treatment from a health facility, if a household was located in a peri-urban area and having a cough are positive predictors of antibacterial use. There is need for targeted education on appropriate antibacterial use in rural communities and hospital settings where over prescription is most likely especially in treating symptoms of ARIs among children under five years.

Indexed as

AmoxicillinAnti-Bacterial AgentsChild, PreschoolCoughCross-Sectional StudiesFemaleHealth SurveysHumansInfantLogistic ModelsMaleMetronidazoleMultivariate AnalysisPrevalenceRespiratory Tract InfectionsRisk FactorsAmoxicillinAnti-Bacterial AgentsMetronidazoleTrimethoprim, Sulfamethoxazole Drug Combination

Identifiers

PMID32574206
PMCPMC7310710
OpenAlexW3036618277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.