Evidence map›Paper›PMID 32573908›Full record

ArticleJournal of applied clinical medical physics2020

A study of the interplay effect for VMAT SBRT using a four-axes motion phantom.

Jermey Leste, Imene Medjahed, François-Xavier Arnaud, Regis Ferrand, Xavier Franceries, Manuel Bardies, Luc Simon

Abstract read
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Article in Journal of applied clinical medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jermey LesteINSERM, Toulouse, France.
Imene MedjahedIUCT-Oncopole, Toulouse, France.
François-Xavier ArnaudIUCT-Oncopole, Toulouse, France.
Regis FerrandINSERM, Toulouse, France.
Xavier FranceriesIUCT-Oncopole, Toulouse, France.
Manuel BardiesINSERM, Toulouse, France.
Luc SimonINSERM, Toulouse, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the accuracy of volumetric modulated arc therapy (VMAT) stereotactic body radiation therapy (SBRT) when treating moving targets (such as lung or liver lesions), focusing on the impact of the interplay effect in the event of complex breathing motion and when a gating window is used.

methodsA dedicated programmable motion platform was implemented. This platform can carry large quality assurance (QA) phantoms and achieve complex three-dimensional (3D) motion. Volumetric modulated arc therapy SBRT plans were delivered with TrueBeam linac to this moving setup and the measured dose was compared to the computed one. Several parameters were assessed such as breathing period, dose rate, dose prescription, shape of the breathing pattern, the use of a planning target volume (PTV) margin, and the use of a gating window.

resultsLoss of dose coverage (D95%) was acceptable in most situations. The doses received by 95% of the CTV, D95% (

conclusionsIn our clinical context, treating lung and liver lesions using VMAT SBRT is reasonable. The interplay effect was moderated and acceptable in all simulated situations.

Indexed as

Lung NeoplasmsRadiosurgeryRadiotherapy, Intensity-ModulatedHumansRadiotherapy DosageRadiotherapy Planning, Computer-Assistedinterplaymotionradiotherapyrespiratorystereotactic body radiation therapy (SBRT)volumetric modulated arc therapy (VMAT)

Identifiers

PMID32573908
PMCPMC7484847

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.