ArticleJournal of veterinary internal medicine2020
Prevalence and characterization of hypoadrenocorticism in dogs with signs of chronic gastrointestinal disease: A multicenter study.
Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- ACVIM-endorsed statement: consensus statement and systematic review on guidelines for the diagnosis and treatment of chronic inflammatory enteropathy in dogs.Journal of veterinary internal medicine · 2026Pooled it
- Evaluation of basal cortisol and the adrenocorticotropic hormone stimulation test in 982 dogs undergoing investigation for hypoadrenocorticism.Journal of veterinary internal medicine · 2026Article
- An extensively hydrolysed protein-based extruded diet in the treatment of dogs with chronic enteropathy and at least one previous diet-trial failure: a pilot uncontrolled open-label study.BMC veterinary research · 2025Article
- Efficacy and side effects of long-term treatment strategies of canine primary hypoadrenocorticism.Frontiers in veterinary science · 2025Article
- Reassessing the role of basal cortisol in ACTH stimulation testing for canine hypoadrenocorticism: insights from a large UK referral and first-opinion dataset.Frontiers in veterinary science · 2025Article
- Comparison of prednisolone and alternative glucocorticoid dosing protocols for canine hypoadrenocorticism: insights from a survey-based study.Frontiers in veterinary science · 2025Article
- Cross-sectional survey of 43,517 dogs in the Dog Aging Project identifies owner-reported lifetime prevalence and characteristics of gastrointestinal disease.Journal of the American Veterinary Medical Association · 2024Article
- Comparison between typical primary and eunatraemic, eukalaemic hypoadrenocorticism: 92 cases.Irish veterinary journal · 2024Article
- Can we predict hypoadrenocorticism in dogs with resting hypocortisolemia? A predictive model based on clinical, haematological, and biochemical variables.Frontiers in veterinary science · 2024Article
- The effects of selected sedatives on basal and stimulated serum cortisol concentrations in healthy dogs.PeerJ · 2024Article
- Atypical hypoadrenocorticism with intact zona glomerulosa of the adrenal cortex after long-term observation: a case report of a dog.The Journal of veterinary medical science · 2023Article
- Characterization of clinicopathologic and abdominal ultrasound findings in dogs with glucocorticoid deficient hypoadrenocorticism.Journal of veterinary internal medicine · 2022Article
- Evaluation of a machine learning tool to screen for hypoadrenocorticism in dogs presenting to a teaching hospital.Journal of veterinary internal medicine · 2022Article
- Diagnosis of canine spontaneous hypoadrenocorticism.Canine medicine and genetics · 2022Review
- Evaluation of resting cortisol concentration testing in dogs with chronic gastrointestinal signs.Journal of veterinary internal medicine · 2022Article
- Urinary cortisol-creatinine ratio in dogs with hypoadrenocorticism.Journal of veterinary internal medicine · 2022Article
- Letter regarding "Utility of the combined use of 3 serologic markers in the diagnosis and monitoring of chronic enteropathies in dogs".Journal of veterinary internal medicine · 2021Article
- Prevalence and characterization of hypoadrenocorticism in dogs with signs of chronic gastrointestinal disease: A multicenter study.Journal of veterinary internal medicine · 2020Article
- Prevalence of eunatremic, eukalemic hypoadrenocorticism in dogs with signs of chronic gastrointestinal disease and risk of misdiagnosis after previous glucocorticoid administration.Journal of veterinary internal medicineArticle
- Clinical findings, treatment, and outcomes in cats with naturally occurring hypoadrenocorticism: 41 cases.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
9 authors at 7 institutions in 4 countries.
Funding
Abstract
backgroundDogs with hypoadrenocorticism (HA) frequently show signs of gastrointestinal disease (SGD). The prevalence of dogs presented for chronic SGD with HA is unknown.
objectivesThe aims of this study were to determine the prevalence of HA in dogs with chronic SGD and to identify clinical and laboratory variables for HA in this population. ANIMALS: One hundred fifty-one dogs with chronic SGD.
methodsIn this multicentered prevalence study a standardized workup was performed in prospectively enrolled dogs with SGD > 3 weeks duration. Basal serum cortisol concentration was measured in every dog with ACTH stimulation test (ACTHST) if basal serum cortisol concentration was <3 μg/dL.
resultsBasal serum cortisol concentration was <3 μg/dL in 80/151 (53%) dogs, <2 μg/dL in 42/151 (28%) dogs, and < 1 μg/dL in 9/151 (6%) dogs. In 6/151 dogs HA was diagnosed based on ACTHST (stimulated serum cortisol concentration < 2 μg/dL), a prevalence of 4%. There was no difference in history, physical examination, and laboratory variables between dogs with HA and those with other causes of chronic SGD. In 4/6 dogs with HA, there was melena or hematochezia indicating gastrointestinal blood loss. Hyperkalemia, hyponatremia, or both was not observed in any dog. CONCLUSION AND CLINICAL IMPORTANCE: The prevalence of HA among dogs with chronic SGD is higher than in the general population. Based on these results, testing adrenal function should be performed as a standard screening test in dogs with chronic SGD to differentiate between HA and chronic enteropathies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.