Evidence map›Paper›PMID 32573431›Full record

ArticleeLife2020

The E2 Marie Kondo and the CTLH E3 ligase clear deposited RNA binding proteins during the maternal-to-zygotic transition.

Michael Zavortink, Lauren N Rutt, Svetlana Dzitoyeva, Jesslyn C Henriksen, Chloe Barrington, Danielle Y Bilodeau, Miranda Wang, Xiao Xiao Lily Chen, Olivia S Rissland

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The many faces of the GID/CTLH E3 ligase complex.Biochemical Society transactions · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Muskelin acts as a substrate receptor of the highly regulatedbioRxiv : the preprint server for biology · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Michael Zavortink *University of Colorado School of Medicine, Aurora, United States.ORCID 0000-0002-7967-1506
Lauren N Rutt *University of Colorado School of Medicine, Aurora, United States.ORCID 0000-0001-9861-207X
Svetlana Dzitoyeva *University of Colorado School of Medicine, Aurora, United States.ORCID 0000-0002-5471-600X
Jesslyn C HenriksenUniversity of Colorado School of Medicine, Aurora, United States.ORCID 0000-0002-7371-2346
Chloe BarringtonUniversity of Colorado School of Medicine, Aurora, United States.ORCID 0000-0002-3884-102X
Danielle Y BilodeauUniversity of Colorado School of Medicine, Aurora, United States.ORCID 0000-0002-8086-4233
Miranda WangUniversity of Toronto, Toronto, Canada.ORCID 0000-0002-8163-4341
Xiao Xiao Lily ChenUniversity of Toronto, Toronto, Canada.ORCID 0000-0003-1529-0568
Olivia S RisslandUniversity of Colorado School of Medicine, Aurora, United States.ORCID 0000-0002-2619-6019
University of Colorado Denver · USUniversity of Toronto · CA

Funding

Exploring the connections between translation and mRNA decayR35GM128680 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI Olivia Selfridge Rissland · 2018 to 2026
$3.7M
NIGMS NIH HHS R35 GM128680
6 · The paper itself

Abstract

The maternal-to-zygotic transition (MZT) is a conserved step in animal development, where control is passed from the maternal to the zygotic genome. Although the MZT is typically considered from its impact on the transcriptome, we previously found that three maternally deposited

Indexed as

AnimalsDEAD-box RNA HelicasesDrosophila melanogasterDrosophila ProteinsProteasome Endopeptidase ComplexRibonucleoproteinsRNA-Binding ProteinsUbiquitinUbiquitin-Protein LigasesZygotecup protein, DrosophilaDEAD-box RNA HelicasesDrosophila ProteinsMe31B protein, DrosophilaProteasome Endopeptidase ComplexRibonucleoproteinsRNA-Binding ProteinsTRAL protein, DrosophilaUbiquitinUbiquitin-Protein Ligaseschromosomesdevelopmental biologyD. melanogastergene expressionmaternal to zygotic transitionpost-transcriptional regulationRNA binding proteinsubiquitin-proteasome system

Identifiers

PMID32573431
PMCPMC7384856
OpenAlexW3036164086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.