Evidence map›Paper›PMID 32573316›Full record

ArticleJournal of the American Heart Association2020

Sex-Based Differences in Unrecognized Myocardial Infarction.

M Yldau van der Ende, Luis Eduardo Juarez-Orozco, Ingmar Waardenburg, Erik Lipsic, Remco A J Schurer, Hindrik W van der Werf, Emelia J Benjamin, Dirk Jan van Veldhuisen, Harold Snieder, Pim van der Harst

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  14. Regulation of autophagy of the heart in ischemia and reperfusion.Apoptosis : an international journal on programmed cell death · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

M Yldau van der EndeDepartment of Cardiology University Medical Center Groningen University of Groningen The Netherlands.
Luis Eduardo Juarez-OrozcoDepartment of Cardiology University Medical Center Groningen University of Groningen The Netherlands.
Ingmar WaardenburgDepartment of Cardiology University Medical Center Groningen University of Groningen The Netherlands.
Erik LipsicDepartment of Cardiology University Medical Center Groningen University of Groningen The Netherlands.
Remco A J SchurerDepartment of Cardiology University Medical Center Groningen University of Groningen The Netherlands.
Hindrik W van der WerfDepartment of Cardiology University Medical Center Groningen University of Groningen The Netherlands.
Emelia J BenjaminDepartment of Medicine Boston University School of Medicine Boston MA.
Dirk Jan van VeldhuisenDepartment of Cardiology University Medical Center Groningen University of Groningen The Netherlands.
Harold SniederDepartment of Epidemiology University Medical Center Groningen University of Groningen The Netherlands.
Pim van der HarstDepartment of Cardiology University Medical Center Groningen University of Groningen The Netherlands.
University of Groningen · NLUniversity Medical Center Groningen · NLBoston University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Myocardial infarction is an important cause of morbidity and mortality in both men and women. Atypical or the absence of symptoms, more prevalent among women, may contribute to unrecognized myocardial infarctions and missed opportunities for preventive therapies. The aim of this research is to investigate sex-based differences of undiagnosed myocardial infarction in the general population. Methods and Results In the Lifelines Cohort Study, all individuals ≥18 years with a normal baseline ECG were followed from baseline visit till first follow-up visit (≈5 years, n=97 203). Individuals with infarct-related changes between baseline and follow-up ECGs were identified. The age- and sex-specific incidence rates were calculated and sex-specific cardiac symptoms and predictors of unrecognized myocardial infarction were determined. Follow-up ECG was available after a median of 3.8 (25th and 75th percentile: 3.0-4.6) years. During follow-up, 198 women experienced myocardial infarction (incidence rate 1.92 per 1000 persons-years) compared with 365 men (incidence rate 3.30;

Indexed as

ElectrocardiographyHealth Status DisparitiesMissed DiagnosisAdultAgedFemaleHeart Disease Risk FactorsHumansIncidenceMaleMiddle AgedMyocardial InfarctionNetherlandsPredictive Value of TestsPrognosisProspective Studiescohort studyepidemiologyincidencesex differencesunrecognized myocardial infarction

Identifiers

PMID32573316
PMCPMC7670510
OpenAlexW3037392792

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.