ArticleJournal of the American Chemical Society2020
Synthesis of (-)-Picrotoxinin by Late-Stage Strong Bond Activation.
Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Computational workflow limits need to 'guess and check' in the synthesis of complex molecules.Nature · 2025Article
- Article
- Substitution, Elimination, and Integration of Methyl Groups in Terpenes Initiated by C-H Bond Functionalization.ACS central science · 2024Article
- The Latest Progress in the Chemistry ofMolecules (Basel, Switzerland) · 2024Review
- Natural Product Synthesis in the 21st Century: Beyond the Mountain Top.ACS central science · 2024Review
- C5 methylation confers accessibility, stability and selectivity to picrotoxinin.Nature communications · 2023Article
- Strategic application of C-H oxidation in natural product total synthesis.Nature reviews. Chemistry · 2023Review
- Spacial Score─A Comprehensive Topological Indicator for Small-Molecule Complexity.Journal of medicinal chemistry · 2023Article
- Carboxylic Acid Directed γ-Lactonization of Unactivated Primary C-H Bonds Catalyzed by Mn Complexes: Application to Stereoselective Natural Product Diversification.Journal of the American Chemical Society · 2022Article
- Unified Total Syntheses of Benzenoid Cephalotane-Type Norditerpenoids: Cephanolides and Ceforalides.Journal of the American Chemical Society · 2022Article
- Catalyst-controlled site-selective methylene C-H lactonization of dicarboxylic acids.Science (New York, N.Y.) · 2022Article
- Total Synthesis of Natural Terpenoids Enabled by Cobalt Catalysis.Frontiers in chemistry · 2022Review
- Revision of the Unstable Picrotoxinin Hydrolysis Product.Angewandte Chemie (International ed. in English) · 2021Article
- GABAJournal, genetic engineering & biotechnology · 2021Review
- Change the channel: CysLoop receptor antagonists from nature.Pest management science · 2021Review
- Natural Product Synthesis through the Lens of Informatics.Accounts of chemical research · 2021Review
- Synthetic, Mechanistic, and Biological Interrogation ofJournal of the American Chemical Society · 2020Article
- Transition Metal-Mediated C-C Single Bond Cleavage: Making the Cut in Total Synthesis.Angewandte Chemie (International ed. in English) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
We report a concise, stereocontrolled synthesis of the neurotoxic sesquiterpenoid (-)-picrotoxinin (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.