Evidence map›Paper›PMID 32573118›Full record

ArticleObesity (Silver Spring, Md.)2020

Walking in the Light: How History of Physical Activity, Sunlight, and Vitamin D Account for Body Fat-A UK Biobank Study.

Brandon S Klinedinst, Nathan F Meier, Brittany Larsen, Yueying Wang, Shan Yu, Jonathan P Mochel, Scott Le, Tovah Wolf, Amy Pollpeter, Colleen Pappas and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Brandon S Klinedinst *Department of Food Science and Human Nutrition, Iowa State University, Ames, Iowa, USA.
Nathan F Meier *Department of Kinesiology, Concordia University, Irvine, California, USA.
Brittany LarsenNeuroscience Program, Iowa State University, Ames, Iowa, USA.
Yueying WangDepartment of Statistics, Iowa State University, Ames, Iowa, USA.
Shan YuDepartment of Statistics, Iowa State University, Ames, Iowa, USA.
Jonathan P MochelDepartment of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA.
Scott LeDepartment of Food Science and Human Nutrition, Iowa State University, Ames, Iowa, USA.
Tovah WolfDepartment of Nutrition and Dietetics, Western Carolina University, Cullowhee, North Carolina, USA.
Amy PollpeterBioinformatics and Computational Biology Program, Iowa State University, Ames, Iowa, USA.
Colleen PappasDepartment of Food Science and Human Nutrition, Iowa State University, Ames, Iowa, USA.
Qian WangDepartment of Food Science and Human Nutrition, Iowa State University, Ames, Iowa, USA.
Karin AllenspachDepartment of Veterinary Clinical Sciences, Iowa State University, Ames, Iowa, USA.
Li WangDepartment of Statistics, Iowa State University, Ames, Iowa, USA.
Daniel RussellDepartment of Human Development and Family Studies, Iowa State University, Ames, Iowa, USA.
David A BennettRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Auriel A WilletteDepartment of Food Science and Human Nutrition, Iowa State University, Ames, Iowa, USA.ORCID 0000-0001-5131-8199
Iowa State University · USConcordia University Irvine · USRush University Medical Center · USUniversity of Iowa · USWestern Carolina University · US

Funding

Insulin Resistance, Biomarkers of Brain Function, and Intermittent Calorie RestrictionR00AG047282 · NIA · IOWA STATE UNIVERSITY · PI WILLETTE, AURIEL · 2016 to 2021
$730k
Medical Research Council MC_PC_17228Medical Research Council MC_QA137853NIA NIH HHS R00 AG047282
6 · The paper itself

Abstract

objectiveThe high prevalence of vitamin D deficiency and obesity drives the need for successful strategies that elevate vitamin D levels, prevent adipogenesis, and stimulate lipolysis. This study provides a theoretical model to evaluate how physical activity (PA) and sunlight exposure influence serum vitamin D levels and regional adiposity. This study hypothesized a posteriori that sunlight is associated with undifferentiated visceral adiposity by increasing the ratio of brown to white adipose tissue.

methodsUsing 10-year longitudinal data, accelerometry, a sun-exposure questionnaire, and regional adiposity quantified by dual-energy x-ray absorptiometry imaging, a structural-equation mediation model of growth curves was constructed with a data-driven methodology.

resultsSunlight and PA conjointly increased serum vitamin D. Changes in vitamin D levels partially mediated how sunlight and PA impacted adiposity in visceral and subcutaneous regions within a subjective PA model. In an objective PA model, vitamin D was a mediator for subcutaneous regions only. Interestingly, sunlight was associated with less adiposity in subcutaneous regions but greater adiposity in visceral regions.

conclusionsSunlight and PA may increase vitamin D levels. For the first time, this study characterizes a positive association between sunlight and visceral adiposity. Further investigation and experimentation are necessary to clarify the physiological role of sunlight exposure on adipose tissue.

Indexed as

SunlightAdipose TissueAgedBiological Specimen BanksExerciseFemaleHumansLongitudinal StudiesMaleMiddle AgedUnited KingdomVitamin DVitamin D

Identifiers

PMID32573118
PMCPMC7501143
OpenAlexW3037638378

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.