Evidence map›Paper›PMID 32573092›Full record

ArticleInternational journal for numerical methods in biomedical engineering2020

Numerical considerations for advection-diffusion problems in cardiovascular hemodynamics.

Sabrina R Lynch, Nitesh Nama, Zelu Xu, Christopher J Arthurs, Onkar Sahni, C Alberto Figueroa

Open access · greenAbstract read
In one paragraph

Article in International journal for numerical methods in biomedical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sabrina R LynchDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-5220-8861
Nitesh NamaDepartment of Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Zelu XuMechanical, Aerospace and Nuclear Engineering, Rensselaer Polytechnic Institute, New York, New York, USA.
Christopher J ArthursSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.
Onkar SahniMechanical, Aerospace and Nuclear Engineering, Rensselaer Polytechnic Institute, New York, New York, USA.
C Alberto FigueroaDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
University of Michigan · USRensselaer Polytechnic Institute · USKing's College London · GB

Funding

American Heart Association-American Stroke Association 20POST35220004Wellcome TrustWellcome Trust 203148/Z/16/ZWellcome Trust 204823/Z/16/Z
6 · The paper itself

Abstract

Numerical simulations of cardiovascular mass transport pose significant challenges due to the wide range of Péclet numbers and backflow at Neumann boundaries. In this paper we present and discuss several numerical tools to address these challenges in the context of a stabilized finite element computational framework. To overcome numerical instabilities when backflow occurs at Neumann boundaries, we propose an approach based on the prescription of the total flux. In addition, we introduce a "consistent flux" outflow boundary condition and demonstrate its superior performance over the traditional zero diffusive flux boundary condition. Lastly, we discuss discontinuity capturing (DC) stabilization techniques to address the well-known oscillatory behavior of the solution near the concentration front in advection-dominated flows. We present numerical examples in both idealized and patient-specific geometries to demonstrate the efficacy of the proposed procedures. The three contributions discussed in this paper successfully address commonly found challenges when simulating mass transport processes in cardiovascular flows.

Indexed as

Cardiovascular SystemHemodynamicsBiological TransportDiffusionHumansbackflow stabilizationcardiovascular simulationconsistent flux boundary conditiondiscontinuity-capturing operatorNeumann inflow boundary conditionscalar advection diffusion

Identifiers

PMID32573092
PMCPMC11129875
OpenAlexW2980747605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.