ArticleGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2021
Clinical significance of endoscopic ultrasonography in diagnosing invasion depth of early gastric cancer prior to endoscopic submucosal dissection.
Article in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31 citing papers in PubMed, 40 citations in OpenAlex.
- Diagnostic evaluation of endoscopic ultrasonography with submucosal saline injection for differentiating between T1a and T1b early gastric cancer.World journal of gastroenterology · 2022Trial
- Blindly Trusting the Stage: The Therapeutic Consequences of Clinical Staging Inaccuracy in Gastric Cancer.Annals of surgical oncology · 2026Article
- Article
- Application value of gastric contrast ultrasonography in gastric tumors.Insights into imaging · 2026Review
- Endoscopic ultrasound in early gastric cancer: Diagnostic accuracy and Tis/T1a lesion over staging risks.World journal of gastroenterology · 2026Article
- Improved diagnostic accuracy and safety of gel-endoscopic ultrasonography for deep submucosal invasion in early gastric cancer.Surgical endoscopy · 2026Article
- A combined approach using conventional endoscopy and endoscopic ultrasonography findings yields a highly accurate diagnosis of T2-muscularis propria gastric cancer.Clinical endoscopy · 2026Article
- Current Role of Artificial Intelligence in the Management of Gastric Cancer.Biomedicines · 2025Review
- Gastric diverticulum misdiagnosed as gastrointestinal stromal tumor: a case description.Quantitative imaging in medicine and surgery · 2025Article
- A randomized trial of combined indocyanine green and endoscopic ultrasound for lymph node evaluation in gastric cancer surgery.Quantitative imaging in medicine and surgery · 2025Article
- Endoscopic Ultrasound (EUS) in Gastric Cancer: Current Applications and Future Perspectives.Diseases (Basel, Switzerland) · 2025Review
- Enhanced diagnostic accuracy of SINE-EUS compared to standard EUS in early colorectal cancer: a self-controlled study.International journal of colorectal disease · 2025Article
- Study on the Accuracy of Miniprobe Ultrasonic Gastroscopy in Determining the Depth of Infiltration of Early Gastric Cancer.Gastroenterology research and practice · 2025Article
- Utilizing a balloon sheath and miniprobe for diagnostic endoscopic ultrasound in eosinophilic esophagitis: a case series.The ultrasound journal · 2024Article
- A novel artificial intelligence-based endoscopic ultrasonography diagnostic system for diagnosing the invasion depth of early gastric cancer.Journal of gastroenterology · 2024Article
- Double contrast-enhanced ultrasonography improves diagnostic accuracy of T staging compared with multi-detector computed tomography in gastric cancer patients.World journal of gastroenterology · 2024Article
- Article
- Validity of Endoscopic Submucosal Dissection for Gastric Cancer Diagnosed as Differentiated Adenocarcinoma Before Treatment Regardless of Lesion Size.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023Article
- The investigation of volatile organic compounds in diagnosing (early) esophageal squamous cell carcinoma and gastric adenocarcinoma.Journal of cancer research and clinical oncology · 2023Article
- Update on diagnosis and treatment of early signet-ring cell gastric carcinoma: A literature review.World journal of gastrointestinal endoscopy · 2023Review
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Authors and funding
9 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimEndoscopic ultrasonography is a reliable diagnostic modality for determining indications of endoscopic submucosal dissection for early gastric cancer. We aimed to clarify the clinical significance of endoscopic ultrasonography in the invasion depth diagnosis of early gastric cancer.
methodsWe retrospectively assessed 1598 consecutive patients with 2001 early gastric cancers who underwent EUS before ESD or surgery between October 2010 and April 2019 at our institution. Lesions were classified according to endoscopic ultrasonography-determined invasion depth as EUS-M/SM1 (lesions confined to sonographic layers 1 and 2 or lesions with changes in sonographic layer 3; depth, < 1 mm) and EUS-SM2 (lesions with changes in sonographic layer 3; depth, ≥ 1 mm). We evaluated the invasion depth determination accuracy of endoscopic ultrasonography and analyzed the clinicopathological features of misdiagnosed early gastric cancer cases.
resultsThe invasion depth determination accuracy was as follows: EUS-M/SM1: pathological T1a/T1b1 early gastric cancer, 97%; EUS-SM2: pathological T1b2 early gastric cancer, 79%. The accuracy, sensitivity, specificity, positive predictive value, and negative predictive value were 95%, 98%, 69%, 97%, and 79%, respectively. In EUS-M/SM1 early gastric cancer, tumor size of ≥ 15 mm, presence of ulceration, and undifferentiated histological type were significantly associated with endoscopic ultrasonography accuracy. In EUS-SM2 early gastric cancer, tumor size of ≥ 30 mm was significantly associated with endoscopic ultrasonography accuracy.
conclusionsEndoscopic ultrasonography is a useful modality in accurately determining the invasion depth of early gastric cancer before endoscopic submucosal dissection.
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