Evidence map›Paper›PMID 32572698›Full record

ArticleDrug delivery and translational research2020

Development of DNA polymer films as a drug delivery system for the treatment of oral cancer.

Cristiano Ceron Jayme, Ananda Ferreira Pires, Antonio Claudio Tedesco

Abstract read
PubMed Publisher
In one paragraph

Article in Drug delivery and translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Cristiano Ceron JaymeDepartment of Chemistry, Center of Nanotechnology and Tissue Engineering, Photobiology and Photomedicine Research Group, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, Ribeirao Preto, São Paulo, 14040-901, Brazil.
Ananda Ferreira PiresDepartment of Chemistry, Center of Nanotechnology and Tissue Engineering, Photobiology and Photomedicine Research Group, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, Ribeirao Preto, São Paulo, 14040-901, Brazil.
Antonio Claudio TedescoDepartment of Chemistry, Center of Nanotechnology and Tissue Engineering, Photobiology and Photomedicine Research Group, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, Ribeirao Preto, São Paulo, 14040-901, Brazil. atedesco@usp.br.ORCID 0000-0003-4198-9321
Universidade de São Paulo · BRUniversidade de Ribeirão Preto · BR

Funding

Financiadora de Estudos e Projetos Project FINEP 01.10.0758.01Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/10237-1Fundação de Amparo à Pesquisa do Estado de São Paulo Thematic project # 2013/50181-1National Institute of Science and Technology Nanobiotechnology project 573880/2008-5Programa Nacional de Apoio à Atenção Oncológica (PRONON) Project FINEP 01.10.0758.01
6 · The paper itself

Abstract

DNA polymer films (DNA-PFs) hold promise for use in drug delivery systems (DDS). In this study, the growth pattern of oral squamous cell carcinoma (OSCC) cells was evaluated on DNA-PFs incorporated with a photoactive compound chlorine aluminum phthalocyanine (DNA-PFs-AlClPc) and the efficacy of DNA-PFs-AlClPc as a DDS for photodynamic therapy (PDT) for the treatment of mucosal cancer. Flow cytometry was used to evaluate cell viability following application of DNA-PFs-AlClPc during PDT; the results demonstrated a positive response to photo stimulation within the range of light doses used (300, 600, and 1200 mJ/cm

Indexed as

Carcinoma, Squamous CellDrug Delivery SystemsMouth NeoplasmsApoptosisCell Line, TumorDNAHumansPhotosensitizing AgentsPolymersDNAPhotosensitizing AgentsPolymersDNA polymeric filmsDrug delivery systemOral cancerPhotodynamic therapy

Identifiers

PMID32572698
OpenAlexW3036190423

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.