Evidence map›Paper›PMID 32572640›Full record

SynthesisClinical oral investigations2020

Pharmacological management of pain after periodontal surgery: a systematic review with meta-analysis.

Leonardo Stephan Caporossi, Cinthia Studzinski Dos Santos, Thayanne Brasil Barbosa Calcia, Maximiliano Sergio Cenci, Francisco Wilker Mustafa Gomes Muniz, Giana da Silveira Lima

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Clinical oral investigations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  4. Single-dose intravenous ibuprofen for acute postoperative pain in adults.The Cochrane database of systematic reviews · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Leonardo Stephan CaporossiGraduate Program in Dentistry, Federal University of Pelotas, 457, Gonçalves Chaves St., Pelotas, Rio Grande do Sul, Brazil.
Cinthia Studzinski Dos SantosGraduate Program in Dentistry, Federal University of Pelotas, 457, Gonçalves Chaves St., Pelotas, Rio Grande do Sul, Brazil.
Thayanne Brasil Barbosa CalciaFaculty of Medicine, Arthur Sá Earp Neto School, 1003, Barão do Rio Branco Ave., Petrópolis, Rio de Janeiro, Brazil.
Maximiliano Sergio CenciDepartment of Operative Dentistry, Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas, 457, Gonçalves Chaves, St., Pelotas, Rio Grande do Sul, Brazil.
Francisco Wilker Mustafa Gomes MunizDepartment of Periodontology, Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas, 457, Gonçalves Chaves St., Pelotas, Rio Grande do Sul, Brazil.
Giana da Silveira LimaDepartment of Operative Dentistry, Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas, 457, Gonçalves Chaves, St., Pelotas, Rio Grande do Sul, Brazil. gianalima@gmail.com.ORCID http://orcid.org/0000-0001-8451-9552
Universidade Federal de Pelotas · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

objectivesTo assess and compare the pharmacological effect of different drugs on pain relief after periodontal surgery. MATERIALS AND

methodsFive databases were searched up to September 2019. The eligible studies comprised randomized clinical trials, involving only adult individuals that received any periodontal surgery and presenting two distinct groups of therapeutic regimens to control postoperative pain. Placebo groups could be included. The risk of bias was assessed with the RoB 2 Cochrane tool and the GRADE system. Meta-analyses were performed using different follow-up and drug comparisons.

resultsOverall, 2398 studies were identified, of which 35 were included. Low risk of bias was determined for the majority of the studies. The meta-analyses showed that the comparison of dexamethasone or non-steroidal anti-inflammatory drugs (NSAID) versus placebo favored the use of both interventions in a follow-up of 1 to 8 h for open flap procedures (OFP). However, no statistical difference was found for the comparison between NSAID and dexamethasone for OFP.

conclusionsPatients may benefit from several pharmacological schemes for pain relief after periodontal surgeries. However, due to the high heterogeneity among studies, no fixed pharmacological protocol could be proposed. CLINICAL RELEVANCE: There is not enough evidence to recommend one therapeutic scheme. However, untreated pain is harmful to the patients and it is not advisable.

Indexed as

Postoperative PainAnti-Inflammatory Agents, Non-SteroidalHumansPain ManagementPain MeasurementPeriodontal DiseasesAnti-Inflammatory Agents, Non-SteroidalAnalgesicsAnti-inflammatory agents non-steroidalOral surgical proceduresPeriodontal diseasesPeriodontics

Identifiers

PMID32572640
OpenAlexW3036301612

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.