ArticleArchives of gynecology and obstetrics2020
Laboratory characteristics of pregnant compared to non-pregnant women infected with SARS-CoV-2.
Article in Archives of gynecology and obstetrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 7 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 7 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- A systematic review and meta-analysis of data on pregnant women with confirmed COVID-19: Clinical presentation, and pregnancy and perinatal outcomes based on COVID-19 severity.Journal of global health · 2021Pooled it
- The Differences in Clinical Presentation, Management, and Prognosis of Laboratory-Confirmed COVID-19 between Pregnant and Non-Pregnant Women: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Transmission of SARS-CoV-2 through breast milk and breastfeeding: a living systematic review.Annals of the New York Academy of Sciences · 2021Pooled it
- Clinical manifestations and perinatal outcomes of pregnant women with COVID-19: a systematic review and meta-analysis.Scientific reports · 2020Pooled it
- Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis.BMJ (Clinical research ed.) · 2020Pooled it
- Clinical features and outcomes of pregnant women with COVID-19: a systematic review and meta-analysis.BMC infectious diseases · 2020Pooled it
- Pregnancy and Breastfeeding During COVID-19 Pandemic: A Systematic Review of Published Pregnancy Cases.Frontiers in public health · 2020Pooled it
- Early Administration of Apelin Could Prevent Heart Failure Following Myocardial Injury; A Systematic Review and Meta-Analysis.Archives of academic emergency medicine · 2025Review
- Comparative analysis of COVID-19 pneumonia in pregnant versus matched non-pregnant women: radiologic, laboratory, and clinical perspectives.Scientific reports · 2024Article
- Reduced control of SARS-CoV-2 infection associates with lower mucosal antibody responses in pregnancy.mSphere · 2024Observational
- Article
- Comparison of clinical features and perinatal outcomes between pre-variant and post-variant periods in pregnant women with SARS-CoV-2: analysis of 1935 cases.Archives of gynecology and obstetrics · 2022Article
- Association of Pregnancy With Coronavirus Cytokine Storm: Systematic Review and Meta-analysis.JMIR pediatrics and parenting · 2022Review
- Pregnancy and COVID-19: The Possible Contribution of Vitamin D.Nutrients · 2022Article
- COVID-19 in pregnant women: An evaluation of clinical symptoms and laboratory parameters based on the 3 trimesters.Saudi medical journal · 2022Article
- Evaluation of clinical and laboratory findings in severe group COVID-19 pregnants without comorbidity.Turkish journal of medical sciences · 2022Article
- Prognosis of COVID-19 in the middle eastern population, knowns and unknowns.Frontiers in microbiology · 2022Review
- Complete Blood Count Peculiarities in Pregnant SARS-CoV-2-Infected Patients at Term: A Cohort Study.Diagnostics (Basel, Switzerland) · 2021Article
- Perspectives on administration of COVID-19 vaccine to pregnant and lactating women: a challenge for low- and middle-income countries.AJOG global reports · 2021Article
- Pregnancy alters interleukin-1 beta expression and antiviral antibody responses during severe acute respiratory syndrome coronavirus 2 infection.American journal of obstetrics and gynecology · 2021Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
key messageLaboratory characteristics of SARS-CoV-2 infection did not differ between pregnant and non-pregnant women. A trend of lower lymphocyte count was observed in the pregnant women group PURPOSE: Laboratory abnormalities, which characterize SARS-CoV-2 infection have been identified, nevertheless, data concerning laboratory characteristics of pregnant women with SARS-CoV-2 are limited. The aim of this study is to evaluate the laboratory characteristics of pregnant compared to non-pregnant women with SARS-CoV-2 infection.
methodsA retrospective cohort study of all pregnant women with SARS-CoV-2 who were examined at the obstetric emergency room in a tertiary medical center between March and April 2020. Patients were compared with non-pregnant women with SARS-CoV-2 matched by age, who were examined at the general emergency room during the study period. All patients were confirmed for SARS-CoV-2 on admission. Clinical characteristics and laboratory results were compared between the groups.
resultsStudy group included 11 pregnant women with SARS-CoV-2, who were compared to 25 non-pregnant controls. Respiratory complaints were the most frequent reason for emergency room visit, and were reported in 54.5% and 80.0% of the pregnant and control groups, respectively (p = 0.12). White blood cells, hemoglobin, platelets, and liver enzymes counts were within the normal range in both groups. Lyphocytopenia was observed in 45.5% and 32% of the pregnant and control groups, respectively (p = 0.44). The relative lymphocyte count to WBC was significantly reduced in the pregnant group compared to the controls [13.6% (4.5-19.3) vs. 26.5% (15.7-29.9); p = 0.003]. C-reactive protein [20(5-41) vs. 14 (2-52) mg/dL; p = 0.81] levels were elevated in both groups but without significant difference between them.
conclusionLaboratory characteristics of SARS-CoV-2 infection did not differ between pregnant and non-pregnant women, although a trend of lower lymphocyte count was observed in the pregnant women group.
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