SynthesisInternational journal of colorectal disease2020
Long-term outcomes of stent-related perforation in malignant colon obstruction: a systematic review and meta-analysis.
Synthesis in International journal of colorectal disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Controversies of colonic stenting in obstructive left colorectal cancer: a critical analysis with meta-analysis and meta-regression.International journal of colorectal disease · 2021Pooled it
- Perforation that Occurred Right After Sigmoid Colon Cancer Stenting.Digestive diseases and sciences · 2026Article
- Clinical Factors for Successful Total Colonoscopy after Self-Expandable Metallic Stent Placement as a Bridge-to-Surgery in Patients with Obstructive Colorectal Cancer.Journal of the anus, rectum and colon · 2026Article
- Contemporary Management of Malignant Bowel Obstruction.Clinics in colon and rectal surgery · 2025Review
- Outcomes of colonic stent as a bridge to surgeryWorld journal of gastrointestinal surgery · 2025Article
- Impact of perforation following self-expandable metal stent as a bridge to surgery for malignant colorectal obstruction: a multicenter study of the Research Group for Stent in the Korean Society of Gastrointestinal Endoscopy.Surgical endoscopy · 2025Article
- Article
- Impact of a novel-covered colonic stent in obstructive colon cancer.Surgical endoscopy · 2024Observational
- A New Self-Expandable Metallic Stent with Low Axial Force and a High Axial Force Zero-Border Shows a Very Low Perforation Rate in Malignant Colorectal Obstruction: A Japanese Multicenter Prospective Study.Journal of clinical medicine · 2024Article
- Colon stenting as a bridge to surgery in obstructive colorectal cancer management.Clinical endoscopy · 2024Review
- Obstructing colorectal cancer: a population-based review of colonic stenting in Queensland, Australia.Annals of coloproctology · 2024Article
- Danish guidelines for treating acute colonic obstruction caused by colorectal cancer-a review.Frontiers in surgery · 2024Review
- Stent as bridge to surgery decreases postoperative complications without worsening oncological outcomes: retrospective unicentric cohort study and stent placement protocol.Surgical endoscopy · 2023Article
- Short- and long-term outcomes of subtotal/total colectomy in the management of obstructive left colon cancer.Annals of coloproctology · 2023Article
- Comparison of long-term outcomes of colonic stenting as a "bridge to surgery" and emergency surgery in patients with left-sided malignant colonic obstruction.Annals of coloproctology · 2023Article
- Oncologic safety of colonic stenting as a bridge to surgery in left-sided malignant colonic obstruction: Current evidence and prospects.World journal of clinical oncology · 2022Review
- Self-expanding metal stent placement and pathological alterations among obstructive colorectal cancer cases.World journal of gastrointestinal endoscopy · 2022Article
- Effect of self-expandable metal stent on morbidity and mortality and oncological prognosis in malignant colonic obstruction: retrospective analysis of its use as curative and palliative treatment.International journal of colorectal disease · 2022Article
- Management of obstructive colon cancer: Current status, obstacles, and future directions.World journal of gastrointestinal oncology · 2021Article
- Short-Term Outcomes of Colorectal Stenting Using a Low Axial Force Self-Expandable Metal Stent for Malignant Colorectal Obstruction: A Japanese Multicenter Prospective Study.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe placement of self-expandable metallic stents as a bridge to surgery in malignant colon obstruction is concerning due to the long-term oncological results reported in recent published studies. The aim of this study was to evaluate the oncological consequences of stent-related perforations in patients with malignant colon obstruction and potentially curable disease.
methodsMEDLINE, Cochrane Library, Ovid and ISRCTN Registry were searched, with no restrictions. We performed five meta-analyses to estimate the pooled effect sizes by using a random-effect model. The outcomes were global, locoregional and systemic recurrence rate and 3 and 5 year-survival rate depending on the presence or absence of stent-related perforation.
resultsThirteen studies (950 patients) were included. The overall rate of stent-related perforation was 8.9%. The global recurrence rate was significantly higher in stent-related perforation group (41.2 vs. 30.8%; OR 1.70; 95%CI: 1.02-2.84; p = 0.04). Locoregional recurrence rate was higher in the perforated group than in the non-perforated group (26.6 vs. 12.5%), with statistically significant differences (OR 2.41; 95% CI:1.33-4.34; p = 0.004). No significant differences were found in systemic recurrence rate (13.6 vs. 20.5%; OR 0.77; 95%CI: 0.35-1.7; p = 0.51); 3-year overall survival rate (65.4 vs. 74.8%; OR 0.63; 95% CI:0.29-1.39; p = 0.25) and 5-year overall survival rate (48.3 vs. 58.6%; OR 0.67; 95%CI: 0.27-1.65; p = 0.38).
conclusionStent-related perforation is associated with an increased risk of global and locoregional recurrence. The successful placement of the stent as a bridge to surgery in the curative purpose of patients with obstructed colon cancer does not exclude the presence of underlying perforation, with the consequent danger of disease spread. PROSPERO registration number: CRD42020152817.
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