Evidence map›Paper›PMID 32572602›Full record

SynthesisInternational journal of colorectal disease2020

Enhanced recovery after surgery in emergency resection for obstructive colorectal cancer: a systematic review and meta-analysis.

Varut Lohsiriwat, Romyen Jitmungngan, Weeraput Chadbunchachai, Patompong Ungprasert

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International journal of colorectal disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07688031 (Efficacy and Safety of Topical Lidocaine 23%/Tetracaine 7% Ointment Versus Placebo for Post-Hemorrhoidectomy Pain), which is not on this map. Cited by 20 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 8 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07688031 phase4completednot on this mapstarted 2023, after this paper: background citation

Efficacy and Safety of Topical Lidocaine 23%/Tetracaine 7% Ointment Versus Placebo for Post-Hemorrhoidectomy Pain: A Double-Blind Randomized Controlled Trial

TypeinterventionalSponsorPontificia Universidad Catolica de ChileRan2023 to 2026Enrolled74ConditionsPain Management, Hemorrhoids Third Degree, Hemorrhoids Fourth Degree, Hemorrhoids Second DegreeArmsLidocaine 23% / Tetracaine 7% topical ointment (compounded), Placebo ointment
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 8 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  3. Enhanced recovery after surgery protocols following emergency intra-abdominal surgery: a systematic review and meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
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  7. [Enhanced recovery after surgery-Does the ERAS concept keep its promises].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
    Pooled it
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  9. Review
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  16. Enhanced recovery protocols in trauma and emergency abdominal surgery: a scoping review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
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  18. Before-and-After Study of the First Four Years of the Enhanced Recovery after Surgery (ERASInternational journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Varut LohsiriwatDepartment of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wang Lung Road, Bangkok, 10700, Thailand. bolloon@hotmail.com.ORCID http://orcid.org/0000-0002-2252-9509
Romyen JitmungnganThe Golden Jubilee Medical Center, Mahidol University, Nakhon Pathom, Thailand.
Weeraput ChadbunchachaiDepartment of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Patompong UngprasertClinical Epidemiology Unit, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Siriraj Hospital · THKhon Kaen University · THMahidol University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEnhanced recovery after surgery (ERAS) improves outcomes after elective colorectal operations. Whether it is beneficial for emergency colorectal surgery is unclear. This study aimed to systematically review and summarize evidence from all studies comparing ERAS versus conventional care in patients having emergency colectomy and/or proctectomy for obstructive colorectal cancer.

methodsEMBASE, MEDLINE, and PUBMED from 1981 to December 2019 were systematically searched. Any studies comparing our primary outcome of interest (length of hospitalization) among patients having emergency resection for obstructive colorectal cancer who received ERAS versus conventional care were selected. Primary outcome was length of hospitalization. Secondary outcomes were gastrointestinal recovery, postoperative complication, 30-day readmission and mortality, and time to start adjuvant therapy.

resultsThree cohort studies with 818 participants (418 received ERAS and 400 received conventional care) were included. Length of hospitalization (mean reduction 3.07 days; 95% CI, - 3.91 to - 2.23) and risk of overall complication (risk ratio 0.78; 95% CI, 0.63 to 0.97) were significantly lower in ERAS than in conventional care. ERAS was also associated with quicker time to gastrointestinal recovery, a lower incidence of ileus, and a shorter interval between operation and commence of adjuvant chemotherapy. There was no significant difference in the rates of anastomotic leakage, surgical site infection, reoperation, readmission, and mortality within 30 days after surgery between groups.

conclusionsERAS had advantages over conventional care in patients undergoing emergency resection for obstructive colorectal cancer-including a shorter length of hospitalization, a lower incidence of overall complication, and a quicker gastrointestinal recovery.

Indexed as

Colorectal NeoplasmsEnhanced Recovery After SurgeryEmergenciesHumansLength of StayPerioperative CarePostoperative ComplicationsRecovery of FunctionColon cancerEmergencyEnhanced recoveryObstructionRectum cancerSurgery

Identifiers

PMID32572602
OpenAlexW3035781495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.