Evidence map›Paper›PMID 32572592›Full record

ArticleEJNMMI research2020

PET imaging of soluble epoxide hydrolase in non-human primate brain with [

Yong Du, Il Minn, Catherine Foss, Wojciech G Lesniak, Feng Hu, Robert F Dannals, Martin G Pomper, Andrew G Horti

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. [European journal of nuclear medicine and molecular imaging · 2023
    Article
  2. Article
  3. Article
  4. Review
  5. Broad Scope and High-Yield Access to Unsymmetrical Acyclic [Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yong DuDivision of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, 601 North Caroline Street, JHOC 3223, Baltimore, MD, 21287, USA. duyong@jhu.edu.ORCID https://orcid.org/0000-0002-0237-6154
Il MinnDivision of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, 601 North Caroline Street, JHOC 3223, Baltimore, MD, 21287, USA.
Catherine FossDivision of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, 601 North Caroline Street, JHOC 3223, Baltimore, MD, 21287, USA.
Wojciech G LesniakDivision of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, 601 North Caroline Street, JHOC 3223, Baltimore, MD, 21287, USA.
Feng HuDivision of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, 601 North Caroline Street, JHOC 3223, Baltimore, MD, 21287, USA.
Robert F DannalsDivision of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, 601 North Caroline Street, JHOC 3223, Baltimore, MD, 21287, USA.
Martin G PomperDivision of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, 601 North Caroline Street, JHOC 3223, Baltimore, MD, 21287, USA.
Andrew G HortiDivision of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, 601 North Caroline Street, JHOC 3223, Baltimore, MD, 21287, USA. ahorti1@jhmi.edu.ORCID https://orcid.org/0000-0003-2290-488X
Johns Hopkins University · US

Funding

PET imaging of soluble epoxide hydrolase (sEH) in human subjectsR33AG054802 · NIA · JOHNS HOPKINS UNIVERSITY · PI HORTI, ANDREW G, POMPER, MARTIN G · 2019 to 2020
$1.1M
PET imaging of soluble epoxide hydrolase (sEH) in human subjectsR21AG054802 · NIA · JOHNS HOPKINS UNIVERSITY · PI HORTI, ANDREW G, POMPER, MARTIN G · 2017 to 2018
$569k
NIA NIH HHS R21 AG054802NIA NIH HHS R33 AG054802NIH HHS AG054802
6 · The paper itself

Abstract

purposeSoluble epoxide hydrolase (sEH) is a promising candidate positron emission tomography (PET) imaging biomarker altered in various disorders, including vascular cognitive impairment (VCI), Alzheimer's disease (AD), Parkinson's disease (PD), stroke, and depression, known to regulate levels of epoxyeicosatrienoic acids (EETs) and play an important role in neurovascular coupling. [

methodsBaboon [

results[

conclusions[

Indexed as

[18F]FNDPCentral nervous systemPapio anubisPositron emission tomographysEH

Identifiers

PMID32572592
PMCPMC7310027
OpenAlexW3036915671

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.